NINDS Alternating Hemiplegia Information Page: NINDS
Article title: NINDS Alternating Hemiplegia Information Page: NINDS
Conditions: Alternating Hemiplegia
What is Alternating Hemiplegia?
Alternating hemiplegia is a rare neurological disorder that develops in childhood, usually before the first 4 years. The disorder is characterized by recurrent but temporary episodes of paralysis on one side of the body. The paralysis can affect eye movements, limbs, or facial muscles. One form of the disorder, identified very recently, has a favorable outlook. It occurs primarily at night, when a child awakens, and is apparently related to migraine. These children have no other mental or neurological impairments. In more serious cases symptoms may include mental impairment, balance and gait difficulties, excessive sweating, and changes in body temperature. Seizures can occur. Sleep helps in the recovery from the periods of paralysis but the paralysis can recur upon waking. The cause of the disorder is unknown.
Is there any
treatment?
Drug therapy including flunarizine may help to reduce
the severity and duration of attacks of paralysis associated with the more
serious form of alternating hemiplegia.
What is the
prognosis?
Children with the benign form of alternating hemiplegia
have a good prognosis. However, those who experience the more severe form
have a poor prognosis because intellectual and mental capacity do not
respond to drug therapy, and balance and gait problems continue. Over
time, walking unassisted becomes difficult or impossible
What research is being
done?
The NINDS supports research on paralytic disorders such as
alternating hemiplegia, with the goals of learning more about these
disorders and finding ways to prevent, treat, and, ultimately, cure them.
International Foundation for Alternating Hemiplegia of Childhood
(IFAHC)
239 Nevada Street
Redwood City, CA 94062
LAEgan@aol.com
http://www.ahckids.org/
Tel:
650-365-5798
Fax: (Same as phone)
National Organization for Rare Disorders (NORD)
P.O. Box 8923
(100 Route 37)
New Fairfield, CT 06812-8923
orphan@rarediseases.org
http://www.rarediseases.org/
Tel:
203-746-6518 800-999-NORD (6673)
Fax: 203-746-6481
This fact sheet is in the public domain. You may copy it.Provided
by:
The National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD
20892
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