Conditions by People Affected (Prevalence or Incidence)
Conditions here are listed by a combined measure of either prevalence or incidence. This gives an approximate measure of the "people affected" by the condition in any year. Prevalence refers to the total pool of people affected, whereas incidence is the annual number of new cases. Lifelong diseases like diabetes can have a low incidence but a large cumulative prevalence count, whereas short-lived diseases like flu can have a high incidence but a low prevalence. For comparison between prevalence and incidence rates see also our conditions by prevalence and conditions by incidence. See also details about prevalence and incidence statistics for more information.
In most cases, the prevalence counts
and incidence rates refer to the USA
or other industrialized nations.
Our estimates show
268
conditions affecting a million or more Americans,
162
conditions between 100,000 and a million,
and
1685
conditions of less than 100,000 US people.
| Condition | Percent | Rate | US People | Data |
| 1. Diarrhea | 100.00% | 1 in 1 | 272 million | almost 100% annually (NIDDK) |
| 2. Common Headache | 90.00% | 1 in 1 | 244.8 million | 90% approximately; almost everyone gets some each year. |
| 3. Respiratory conditions | 78.90% | 1 in 1 | 214.6 million | 78.9 per 100 (NHIS96) |
| 4. Dental caries | 55.57% | 1 in 2 | 151.2 million | 2,534,161 annual cases in Victoria 1996 (DHS-VIC) |
| 5. Cytomegalovirus | 50.00% | 1 in 2 | 136 million | 50% approximately; almost half of young adults (NIAID) |
| 6. Cold sores | 50.00% | 1 in 2 | 136 million | estimated 50 to 80% of Americans have HSV-1 |
| 7. Refractive Eye Disorders | 44.12% | 1 in 2 | 120 million | 120 million people |
| 8. High Cholesterol | 37.13% | 1 in 3 | 101 million | estimated 101 million Americans have cholesterol >= 200 mg/dL (CDC) |
| 9. Infectious Diarrhea | 36.40% | 1 in 3 | 99 million | 99 million new cases in the USA 1980 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 10. Flu | 36.00% | 1 in 3 | 97.9 million | 36 per 100 (NHIS96); 35 million annually up to 50 million annually (NIAID/CDC); 10-20% yearly (NIAID) |
| 11. Overweight | 35.70% | 1 in 3 | 97.1 million | 97.1 million American adults |
| 12. Chronic Illness | 33.09% | 1 in 3 | 90 million | 90 million people in USA (CDC) |
| 13. Food poisoning | 27.94% | 1 in 3 | 76 million | about 76 million cases annually in USA (NIDDK) |
| 14. Myopia | 25.74% | 1 in 3 | 70 million | 70 million Americans; over 25 percent of all adult Americans. |
| 15. Insulin Resistance | 25.00% | 1 in 4 | 68 million | about 25% of the USA population have insulin resistance |
| 16. Metabolic Syndrome | 25.00% | 1 in 4 | 68 million | about 25% of the USA population have insulin resistance |
| 17. Genital herpes | 24.63% | 1 in 4 | 67 million | 67 million people (NIAID) |
| 18. Sexually Transmitted Diseases | 23.90% | 1 in 4 | 65 million | 65 million people living with an incurable STD (CDC) |
| 19. Common cold | 22.79% | 1 in 4 | 62 million | 62 million cases (NIAID); 23.6 per 100 (NHIS96); estimated 1 billion colds in the USA annually; Children get 6-10 yearly, adults 2-4 yearly; over 60's less than 1 a year. |
| 20. Cardiovascular diseases | 22.72% | 1 in 4 | 61.8 million | 61,800,000 cases in the USA (American Heart Association, 2004) |
| 21. Hyperopia | 22.40% | 1 in 4 | 60.9 million | 22.4% of population self-reported having long-sightedness in Australia 2001 (ABS 2001 National Health Survey, Australia’s Health 2004, AIHW) |
| 22. Smoking | 22.30% | 1 in 4 | 60.7 million | 22.3% of Americans smoke (CDC); 23 million American women smoke (NHLBI) |
| 23. Mental illness | 22.10% | 1 in 4 | 60.1 million | about 22.1 percent of American adults annually or 44.3 million people (NIMH) |
| 24. Toxoplasmosis | 22.06% | 1 in 4 | 60 million | More than 60 million in USA but few have symptoms (DPD) |
| 25. Digestive Diseases | 22.06% | 1 in 4 | 60 million | 60 to 70 million cases in the USA 1985 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447) |
| 26. Injury | 21.69% | 1 in 4 | 59 million | 59 million cases (IOM) |
| 27. Epstein-Barr virus | 20.00% | 1 in 5 | 54.4 million | as many as 20% of people carry the virus in their throats |
| 28. Hypertension | 18.38% | 1 in 5 | 50 million | 50 million Americans (NHLBI); 217 per 1000 (NHIS95) |
| 29. Dandruff | 18.38% | 1 in 5 | 50 million | 50 million |
| 30. Allergies | 18.38% | 1 in 5 | 50 million | 50-60 million (NIAID); 9-16% (NIAID); 50 million cases annually (NIAID); 10% of American women (NHWIC); 8,526,000 children respiratory allergies (NHIS-97); 7,304,000 children non-respiratory allergies (NHIS-97) |
| 31. Headache | 16.54% | 1 in 6 | 45 million | 45 million Americans get chronic headaches. 20 million American women (NWHIC). |
| 32. Chronic headache | 16.54% | 1 in 6 | 45 million | estimated 45 million Americans (NINDS) |
| 33. Astigmatism | 16.54% | 1 in 6 | 45 million | 45 million Americans (dubious estimate based on "two thirds of people with myopia also have astigmatism") |
| 34. Anxiety Disorders | 16.40% | 1 in 6 | 44.6 million | estimated 16.4% adults (USSG); 19.1 million American adults (NIMH); 13.3% of adults (NIMH) |
| 35. Impaired glucose tolerance | 15.07% | 1 in 6 | 41 million | estimated 41 million people aged 40-74 have pre-diabetes in the US 1988-94 (National Diabetes Statistics fact sheet, NIDDK, 2003) |
| 36. Premenstrual syndrome | 15.00% | 1 in 6 | 40.8 million | 30-40% women suffer some impairment of daily activity (NWHIC); 75% women have some symptoms; 3-8% women have severe PMS (NWHIC). |
| 37. Hives | 15.00% | 1 in 6 | 40.8 million | about 15% Americans each year (NWHIC) |
| 38. Orthopedic disorders | 14.90% | 1 in 6 | 40.5 million | 149 per 1000 - NHIS95 |
| 39. Sleep disorders | 14.71% | 1 in 6 | 40 million | approximately 40 million Americans (NHLBI) |
| 40. Obesity | 14.63% | 1 in 6 | 39.8 million | 39.8 million American adults; more than 57% of American adults are overweight (CDC) |
| 41. Arthritis | 13.60% | 1 in 7 | 37 million | 37 million Americans (NIAMS) |
| 42. Sinusitis | 13.60% | 1 in 7 | 37 million | 37 million annually in the USA; 33 million reported to CDC (NIAID) |
| 43. Hay fever | 12.87% | 1 in 7 | 35 million | 35 million Americans (NIAID: pollen allergies) |
| 44. Pollen allergy | 12.87% | 1 in 7 | 35 million | estimated 35 million Americans with pollen allergies (NIAID) |
| 45. Chronic Sinusitis | 12.83% | 1 in 7 | 34.9 million | 12.6% (NIAID); 152 per 1000 - NHIS95 |
| 46. Insomnia | 11.76% | 1 in 8 | 32 million | 32 million (unreliable estimate) |
| 47. Chronic lower respiratory diseases | 11.76% | 1 in 8 | 32 million | estimated 32 million including 15 million undiagnosed |
| 48. Lung conditions | 11.03% | 1 in 9 | 30 million | more than 30 million Americans with chronic lung diseases (NWHIC) |
| 49. Impotence | 11.03% | 1 in 9 | 30 million | 30 million men (NIDDK) |
| 50. Lactose Intolerance | 11.03% | 1 in 9 | 30 million | 30 million people to 50 million people (NIDDK 1994); about 25% of population (1994/NIDDK) |
| 51. Osteoporosis | 10.29% | 1 in 9 | 28 million | 28 million Americans (10 million with osteoporosis; 18 million with low bone mass); eight million American women and 2 million men (NWHIC) |
| 52. Migraine | 10.29% | 1 in 9 | 28 million | 28 million Americans (NINDS) |
| 53. Moles | 10.00% | 1 in 10 | 27.2 million | common; most people have 10-40 moles. |
| 54. Molluscum contagiosum | 10.00% | 1 in 10 | 27.2 million | Common. |
| 55. Scabies | 10.00% | 1 in 10 | 27.2 million | common |
| 56. Retroverted uterus | 10.00% | 1 in 10 | 27.2 million | about 1 in 5 women |
| 57. Subfertility | 10.00% | 1 in 10 | 27.2 million | about 1 in 10 couples |
| 58. Allergic rhinitis | 10.00% | 1 in 10 | 27.2 million | 10% of the population with allergic rhinitis/hay fever in the US (Mayo Clinic) |
| 59. Otosclerosis | 10.00% | 1 in 10 | 27.2 million | as many as 10% of Caucasians have the condition but most do not get symptoms; about 1 in 100 cases actually lose hearing from otosclerosis |
| 60. Extra Nipples | 10.00% | 1 in 10 | 27.2 million | about 1 in 10 people but most are small and mistaken for freckles or moles |
| 61. Depressive disorders | 9.50% | 1 in 10 | 25.8 million | 9.5 percent of adult Americans (NIMH) |
| 62. Rare diseases | 9.19% | 1 in 10 | 25 million | about 25 million Americans (ORD); each disease less than 200,000 Americans by definition. |
| 63. Presbyopia | 9.00% | 1 in 11 | 24.5 million | 9.0% of population self-reported having presbyopia in Australia 2001 (ABS 2001 National Health Survey, Australia’s Health 2004, AIHW) |
| 64. Back Impairment | 8.50% | 1 in 11 | 23.1 million | 85 per 1000 - NHIS95 (deformity or orthopedic impairment of back) |
| 65. Heart disease | 8.09% | 1 in 12 | 22 million | 22 million adults in the US 2000 (Centers for Disease Control and Prevention) |
| 66. Hearing Impairment | 8.09% | 1 in 12 | 22 million | 22 million; 158 per 1000 (NHIS95) |
| 67. Thyroid disorders | 7.35% | 1 in 13 | 20 million | 20 million Americans (NWHIC) |
| 68. Human Papillomavirus | 7.35% | 1 in 13 | 20 million | 20 million Americans currently infected (NIAID; CDC 2001) |
| 69. Osteoarthritis | 7.35% | 1 in 13 | 20 million | 20 million people (NIAMS); more than 16 million people (NWHIC) |
| 70. Mood disorders | 7.10% | 1 in 14 | 19.3 million | estimated 7.1% adults (USSG) |
| 71. Ischemic heart disease | 6.80% | 1 in 14 | 18.5 million | 68 per 1000 (NHIS95) |
| 72. Sleep apnea | 6.62% | 1 in 15 | 18 million | estimated 18 million Americans (NHLBI) |
| 73. Asthma | 6.40% | 1 in 15 | 17.4 million | 6.4% USA (NIAID); 17 million Americans (NIAID) including 5 million children; 8.1 million children (NHIS-97), 51 per 1000 - NHIS95; 14.5 million; 5% of population (NWHIC); 14.9 million in 1995 (NHLBI) |
| 74. Acne | 6.25% | 1 in 16 | 17 million | 17 million Americans, almost 85% of people 12-24 years of age. |
| 75. Diabetes | 5.88% | 1 in 17 | 16 million | 16 million Americans with 10.3 million diagnosed and 8.1 million women (NWHIC); 65 per 1000 - NHIS95; 8 million - perhaps 16 million if include not-yet-diagnosed. |
| 76. Type 2 diabetes | 5.88% | 1 in 17 | 16 million | 16 million Americans (NWHIC, includes undiagnosed); 7.2 million (actually diagnosed) |
| 77. Gallstones | 5.88% | 1 in 17 | 16 million | 16 to 22 million people in the USA 1976-87 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, US Government Printing Office, NIDDK, 1994) |
| 78. Alcoholism | 5.55% | 1 in 18 | 15.1 million | estimated 15.1 million people: 15.1 million alcohol-abusing or alcohol-dependent individuals and 4.6 million are women (NWHIC); nearly 14 million Americans (NIAAA) |
| 79. Alcohol abuse | 5.55% | 1 in 18 | 15.1 million | estimated 15.1 million people: 15.1 million alcohol-abusing or alcohol-dependent individuals and 4.6 million are women (NWHIC); nearly 14 million Americans (NIAAA) |
| 80. Eczema | 5.51% | 1 in 18 | 15 million | 15 million people (NIAMS); 10% infants/children estimated (NIAMS); 9% (NIAID); 8.5 million |
| 81. Gynecomastia | 5.51% | 1 in 18 | 15 million | 15 million - 15% of adult men to some extent (unreliable estimate) |
| 82. Heartburn | 5.51% | 1 in 18 | 15 million | 15 million Americans have it daily (NIDDK) |
| 83. Depression | 5.30% | 1 in 18 | 14.4 million | estimated 5.3% adults (USSG); 17 million people; approximately 4% of adolescents get seriously depressed (NIMH); annually 12% of women ; 7% of men; lifetime risk of an episode for women 20%. 3-4 million men USA. |
| 84. Arrhythmias | 5.30% | 1 in 18 | 14.4 million | 53 per 1000 (NHIS95: heart rhythm disorders); 21 per 1000 (NHIS95: heart murmurs) |
| 85. Urinary stones | 5.20% | 1 in 19 | 14.1 million | 5.2% of adults in the USA 1988-1994 (Weighted Analysis of 1988-1994 National Health and Nutrition Survey, 2003) |
| 86. Raynaud's phenomenon | 5.00% | 1 in 20 | 13.6 million | 5-10% (NIAMS estimate). Scleroderma-related disorders including Raynaud's phenomenon between 250,000 and 992,500. |
| 87. Uterine fibroids | 5.00% | 1 in 20 | 13.6 million | 10-20% women (NWHIC) |
| 88. Endometriosis | 5.00% | 1 in 20 | 13.6 million | 10 to 20 percent of American women of childbearing age have endometriosis (NIDCD); up to 2 million women in the UK. |
| 89. Red-green color blindness | 5.00% | 1 in 20 | 13.6 million | about 10% of males |
| 90. Chronic Obstructive Pulmonary Disease | 4.96% | 1 in 20 | 13.5 million | 13.5 million Americans (NHLBI) |
| 91. Coronary heart disease | 4.85% | 1 in 20 | 13.2 million | estimated 13,200,000 in the USA 2001 (American Heart Association, 2004) |
| 92. Urinary Incontinence | 4.78% | 1 in 20 | 13 million | 13 million adults (NIDDK); 1 in 10 over 65 (NWHIC). |
| 93. Rosacea | 4.78% | 1 in 20 | 13 million | 13 million people in the United States (NIAMS) |
| 94. Acute Bronchitis | 4.60% | 1 in 21 | 12.5 million | 4.6 per 100 (NHIS96: acute bronchitis); 14.2 million cases annually |
| 95. Varicose veins | 4.50% | 1 in 22 | 12.2 million | 45 per 1000 (NHIS95) |
| 96. Tinnitus | 4.50% | 1 in 22 | 12.2 million | 45 per 1000 (NHIS95); 12 million Americans |
| 97. Chronic Bronchitis | 4.45% | 1 in 22 | 12.1 million | 12.1 million Americans (NHLBI) |
| 98. Obstructive sleep apnea | 4.41% | 1 in 22 | 12 million | 12 million Americans |
| 99. Genetic Disease | 4.41% | 1 in 22 | 12 million | 12 million Americans - unreliable estimate, (perhaps 2.5% births) |
| 100. Phobias | 4.23% | 1 in 23 | 11.5 million | 11.5 million adults (NIMH); 8.0% adults (NIMH) |
| 101. Iron deficiency anemia | 4.12% | 1 in 24 | 11.2 million | 187,979 annual cases in Victoria 1996 (DHS-VIC); 20% women of childbearing age; 2% adult men (NWHIC) |
| 102. Cornea disorders | 4.04% | 1 in 24 | 11 million | 11,000,000 people experience corneal disorders such as herpes or dry eye in the US (Research to Prevent Blindness, NISE, NSF) |
| 103. Dysthymia | 4.01% | 1 in 24 | 10.9 million | about 10.9 million American adults (NIMH); estimated 1.6% adults (USSG) |
| 104. Presbycusis | 3.90% | 1 in 25 | 10.6 million | 30-35% over 65 have some hearing loss, 40-50% over 70. |
| 105. Hemorrhoids | 3.82% | 1 in 26 | 10.4 million | 10.4 million people in the USA 1983-87 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 106. Social phobia | 3.70% | 1 in 27 | 10.1 million | 5.3 million adult Americans (NIMH); 3.7% adults (NIMH); 2.0% adults (USSG) |
| 107. Latent tuberculosis | 3.68% | 1 in 27 | 10 million | estimated 10 to 15 million people in USA (NIAID) |
| 108. Jaw conditions | 3.68% | 1 in 27 | 10 million | estimated 10 million women in the USA (NWHIC) |
| 109. Traveler's diarrhea | 3.68% | 1 in 27 | 10 million | estimated 10 million (DBMD) |
| 110. Enteroviruses | 3.68% | 1 in 27 | 10 million | estimated 10-15 million cases annually in USA (DVRD) |
| 111. Age-related macular degeneration | 3.68% | 1 in 27 | 10 million | 10,000,000 people have reduced vision due to age-related macular degeneration in the US (Research to Prevent Blindness, NISE, NSF) |
| 112. Post-traumatic stress disorder | 3.60% | 1 in 27 | 9.8 million | 5.2 million adult Americans (NIMH); 3.6% adults (NIMH); about 30% of war veterans. |
| 113. Indigestion | 3.50% | 1 in 28 | 9.5 million | 35 per 1000 - NHIS95 (frequent indigestion) |
| 114. Dermatitis | 3.30% | 1 in 30 | 8 million | 33 per 1000 (NHIS95) |
| 115. Insect sting allergies | 3.30% | 1 in 30 | 8 million | 3.3% (NIAID); up to 5% of the population (NHWIC) |
| 116. Bursitis | 3.20% | 1 in 31 | 8.7 million | 32 per 1000 (NHIS95) |
| 117. Autoimmune diseases | 3.13% | 1 in 31 | 8.5 million | 8,511,845 people in the USA 1996 1 |
| 118. Dry skin | 3.10% | 1 in 32 | 8.4 million | 31 per 1000 - NHIS95 (trouble with dry/itching skin) |
| 119. Disc Disorders | 3.10% | 1 in 32 | 8.4 million | 31 per 1000 (NHIS95: intervertebrate disc disorders) |
| 120. Acute urinary conditions | 3.09% | 1 in 32 | 8.4 million | 8.405 million new conditions (NIDDK) |
| 121. Acute Nonulcer dyspepsia | 3.01% | 1 in 33 | 8.2 million | 8.2 million new cases (1988/NIDDK) |
| 122. Paget's disease of bone | 3.00% | 1 in 33 | 8.2 million | about 3% of people aged over 40; 10% by age 80. |
| 123. Congenital conditions | 3.00% | 1 in 33 | 8.2 million | 3-4% of babies (NWHIC) |
| 124. Gastroesophageal Reflux Disease | 3.00% | 1 in 33 | 8.2 million | 3-7% of the population in the USA 1985 for "GERD and related esophageal disorders" (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 125. Urinary tract infections (child) | 3.00% | 1 in 33 | 8.2 million | 3% of girls and 1% of boys before age 11 |
| 126. Cerebrovascular Conditions | 3.00% | 1 in 33 | 8.2 million | 30 per 1000 - NHIS95 |
| 127. Generalized anxiety disorder | 2.80% | 1 in 35 | 7.6 million | 4 million adult Americans (NIMH); 2.8% adults (NIMH); estimated 3.4% adults (USSG) |
| 128. Heart attack | 2.76% | 1 in 36 | 7.5 million | 7.5 million people with AMI (NHLBI) |
| 129. Squint | 2.76% | 1 in 36 | 7.5 million | 7,500,000 people suffer from strabismus or cross eyes in the US (Research to Prevent Blindness, NISE, NSF) |
| 130. Kidney disease | 2.72% | 1 in 36 | 7.4 million | 7.4 million adults in the USA 1988-94 (American Journal of Kidney Disease) |
| 131. Prostate conditions | 2.60% | 1 in 38 | 7.1 million | 52 per 1000 men - NHIS95; 2,803 million men (NIDDK) |
| 132. Ingrown nails | 2.60% | 1 in 38 | 7.1 million | 26 per 1000 - NHIS95 (trouble with ingrown nails) |
| 133. Middle ear infection | 2.57% | 1 in 38 | 7 million | 7 million annually |
| 134. Callus | 2.50% | 1 in 40 | 6.8 million | 25 per 1000 - NHIS95 (trouble with corns or calluses) |
| 135. Corns | 2.50% | 1 in 40 | 6.8 million | 25 per 1000 - NHIS95 (trouble with corns or calluses) |
| 136. Polycystic ovary syndrome | 2.50% | 1 in 40 | 6.8 million | 5-10% women of childbearing age (20-40); 30% of women have some PCOS symptoms (NWHIC). |
| 137. Fecal incontinence | 2.39% | 1 in 41 | 6.5 million | 6.5 million Americans |
| 138. Angina | 2.35% | 1 in 42 | 6.4 million | 6.4 million Americans (NHLBI) |
| 139. Specific phobias | 2.32% | 1 in 43 | 6.3 million | estimated 6.3 million adult Americans (NIMH); estimated 8.3% adults (USSG) |
| 140. Occupational Injuries | 2.32% | 1 in 43 | 6.3 million | 6.3 million workers in 1994 (CDC-OC) |
| 141. Obsessive-compulsive disorder | 2.30% | 1 in 43 | 6.3 million | 3.3 million adult Americans (NIMH); 2.3% adults (NIMH); 1 in 50 people (NWHIC); 2.4% adults (USSG) |
| 142. Cystitis | 2.28% | 1 in 43 | 6.2 million | 6.2 million adults self-reported having a bladder infection for more than 3 months in the US 1988-1994 (Weighted Analysis of 1988-1994, NHANES, NIDDK) |
| 143. Infertility | 2.24% | 1 in 44 | 6.1 million | 6.1 million people in 1997 (NWHIC); 5.3 million Americans or 9% of reproductive age (NWHIC/American Society for Reproductive Medicine) |
| 144. Back pain | 2.21% | 1 in 45 | 6 million | 6 million cases annually (unreliable estimate) |
| 145. Chest pain | 2.21% | 1 in 45 | 6 million | 6 million cases annually (unreliable estimate) |
| 146. Nonulcer dyspepsia | 2.13% | 1 in 46 | 5.8 million | 5.8 million people in the USA 1988 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, 1994) |
| 147. Anti-Social Personality Disorder | 2.10% | 1 in 47 | 5.7 million | estimated 2.1% adults (USSG) |
| 148. Periodontitis | 2.07% | 1 in 48 | 5.6 million | 94,482 annual cases in Victoria 1996 (DHS-VIC) |
| 149. Cataracts | 2.02% | 1 in 49 | 5.5 million | 5,500,000 people have a cataract interfering with their vision in the US (Research to Prevent Blindness, NISE, NSF) |
| 150. Psoriasis | 2.02% | 1 in 49 | 5.5 million | 5.5 million people in the USA (NIAMS) |
| 151. Autoimmune thyroid diseases | 2.00% | 1 in 50 | 5.4 million | 4 out of 100 women some type of autoimmune thyroid disease |
| 152. Borderline Personality Disorder | 2.00% | 1 in 50 | 5.4 million | 2 percent of adults (NIMH) |
| 153. Cyclic vomiting syndrome | 2.00% | 1 in 50 | 5.4 million | 1 in 50 children (perhaps) |
| 154. Penicillin allergy | 2.00% | 1 in 50 | 5.4 million | 2-3% of people (2-3% of hospitalized patients) |
| 155. Mitral-valve prolapse | 2.00% | 1 in 50 | 5.4 million | 2% of the adult population (NHLBI estimate) |
| 156. Bunions | 1.92% | 1 in 51 | 5.2 million | 19.25 per 1000 - NHIS95 (trouble with bunions) |
| 157. Female genital disorders | 1.90% | 1 in 52 | 5.2 million | 38 per 1000 women (NHIS95) |
| 158. Trichomoniasis | 1.84% | 1 in 54 | 5 million | 5 million cases annually in the USA (CDC 2001) |
| 159. Irritable bowel syndrome | 1.84% | 1 in 54 | 5 million | 5 million in the USA 1987 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, US Government Printing Office, 1994); 11 per 1000 (NHIS95) |
| 160. Peptic Ulcer | 1.84% | 1 in 54 | 5 million | 5 million in the USA 1987 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, 1994) |
| 161. Eating disorders | 1.84% | 1 in 54 | 5 million | 5 million women (NWHIC); 1-4% of young women |
| 162. Pneumonia | 1.76% | 1 in 56 | 4.8 million | 4.8 million annual cases (1996); 1.8 per 100 (NHIS96) |
| 163. Heart failure | 1.76% | 1 in 56 | 4.8 million | 4.8 million (NHLBI); 2 to 3 million Americans (NHLBI) |
| 164. Congestive Heart Failure | 1.76% | 1 in 56 | 4.8 million | 4.8 million Americans (NHLBI); 2% age 40-59; 5% age 60-69; 10% over 70's |
| 165. Panic disorder | 1.70% | 1 in 58 | 4.6 million | approximately 2.4 million Americans (NIMH) |
| 166. Atherosclerosis | 1.70% | 1 in 58 | 4.6 million | 17 per 1000 - NHIS95 |
| 167. Learning disabilities | 1.69% | 1 in 59 | 4.6 million | 4.6 million children (NHIS-97) |
| 168. Stroke | 1.69% | 1 in 59 | 4.6 million | estimated 4.6 million (NHLBI) |
| 169. Automobile accidents injury | 1.68% | 1 in 59 | 4.6 million | 4,563,000 cases requiring emergency department visits in 2000 (CDC) |
| 170. Abdominal Hernia | 1.65% | 1 in 60 | 4.5 million | 4.5 million people in the USA 1988-90 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 171. Constipation | 1.62% | 1 in 61 | 4.4 million | 4.4 million people in the USA 1983-87 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 172. Edema | 1.60% | 1 in 62 | 4.4 million | 1.6% of population self-reported having oedema in Australia 2001 (ABS 2001 National Health Survey, Australia’s Health 2004, AIHW) |
| 173. Tachycardia | 1.60% | 1 in 62 | 4.4 million | 16 per 1000 (NHIS95) |
| 174. Falls | 1.52% | 1 in 65 | 4.1 million | 69,264 annual cases in Victoria 1996 (DHS-VIC) |
| 175. Kidney conditions | 1.50% | 1 in 66 | 4.1 million | 15 per 1000 (NHIS95: "kidney trouble") |
| 176. Undescended Testicle | 1.50% | 1 in 66 | 4.1 million | 3% of male babies; about 30% of premature male babies. |
| 177. Childbirth | 1.49% | 1 in 67 | 4 million | 4,043,000 annual live births ending Aug 2001 (NVSR 50:7 2002); 4,058,814 annually in 1999 in USA (CDC) |
| 178. Shoulder conditions | 1.47% | 1 in 68 | 4 million | about 4 million annual cases in USA (NIAMS) |
| 179. Alzheimer's Disease | 1.47% | 1 in 68 | 4 million | more than 4 million Americans (CDC); estimated 4 million people in the U.S (NHWIC) |
| 180. Chlamydia | 1.47% | 1 in 68 | 4 million | estimated 4 million cases (NIAID/CDC) [4-8 million cases] including undiagnosed (about 600,000 diagnosed). |
| 181. Pregnancy | 1.47% | 1 in 68 | 4 million | more than 4 million; 1 million adolescent U.S. females become pregnant every year |
| 182. Drug abuse | 1.47% | 1 in 68 | 4 million | more than 4 million women need treatment for drug abuse (NWHIC) |
| 183. Chronic Hepatitis C | 1.47% | 1 in 68 | 4 million | Almost 4 million Americans have antibodies indicating infection or prior exposure (NIDDK). |
| 184. Deafness | 1.47% | 1 in 68 | 4 million | 4 million people (unreliable estimate) |
| 185. Fibromyalgia | 1.36% | 1 in 73 | 3.7 million | 3.7 million Americans (NIAMS) |
| 186. Open Wound | 1.32% | 1 in 75 | 3.6 million | 60,052 annual cases of open wounds in Victoria 1996 (DHS-VIC) |
| 187. Color blindness | 1.30% | 1 in 76 | 3.5 million | 13 per 1000 - NHIS95 |
| 188. Anemia | 1.29% | 1 in 77 | 3.5 million | 3.5 million (NHLBI) |
| 189. Attention Deficit Hyperactivity Disorder | 1.21% | 1 in 82 | 3.3 million | 3.3 million children have ADD in USA (NHIS-97); estimated 2 million American children; 3 to 5 percent of all children (NIMH). |
| 190. Rheumatic fever | 1.20% | 1 in 83 | 3.3 million | 12 per 1000 (NHIS95) |
| 191. Bipolar disorder | 1.20% | 1 in 83 | 3.3 million | 1.2 percent of the population; 2.3 million adult Americans (NIMH) |
| 192. Colitis | 1.20% | 1 in 83 | 3.3 million | 12 per 1000 (NHIS95: "enteritis or colitis") |
| 193. Enteritis | 1.20% | 1 in 83 | 3.3 million | 12 per 1000 (NHIS95: "enteritis or colitis") |
| 194. Acute rheumatic fever | 1.20% | 1 in 83 | 3.3 million | 12 per 1000 (NHIS95) |
| 195. Agoraphobia | 1.18% | 1 in 84 | 3.2 million | approximately 3.2 million American adults ages 18 to 54 (NIMH); estimated 4.9% adults (USSG) |
| 196. Bladder conditions | 1.15% | 1 in 86 | 3.1 million | 3.139 million cases (chronic, NIDDK); 25 per 1000 - NHIS95 (bladder disorders) |
| 197. Graves Disease | 1.12% | 1 in 89 | 3 million | 3,048,636 people in the USA 1996 1; 1.3 million people (NWHIC) |
| 198. Pubic lice | 1.10% | 1 in 90 | 3 million | 3 million new cases annually estimated (NIAID) |
| 199. Rotavirus | 1.10% | 1 in 90 | 3 million | 3 million cases in the USA each year. |
| 200. Von Willebrand disease | 1.10% | 1 in 90 | 3 million | estimated 3 million mostly undiagnosed |
| 201. Open-angle glaucoma | 1.10% | 1 in 90 | 3 million | about 3 million Americans, many not yet diagnosed. |
| 202. Peanut allergies | 1.10% | 1 in 90 | 3 million | 3 million Americans (peanut and tree nut combined; NIAID) |
| 203. Dental conditions | 1.10% | 1 in 90 | 2 million | 1.1 per 100 (NHIS96: acute dental conditions) |
| 204. Stuttering | 1.00% | 1 in 100 | 2.7 million | about 1% of adults |
| 205. Deuteranopia | 1.00% | 1 in 100 | 2.7 million | about 1% of white males |
| 206. Protanopia | 1.00% | 1 in 100 | 2.7 million | about 1% of white males |
| 207. Food allergies | 1.00% | 1 in 100 | 2.7 million | 1% of the adult population have a true immune reaction to food (NHWIC) |
| 208. Latex allergies | 1.00% | 1 in 100 | 2.7 million | 1-6% (NIAID) |
| 209. Speech impairment | 1.00% | 1 in 100 | 2.7 million | 10 per 1000 (NHIS95) |
| 210. Gastritis | 0.99% | 1 in 100 | 2.7 million | 2.7 million people in the USA 1988 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 211. Rheumatoid arthritis | 0.92% | 1 in 108 | 2.5 million | 2.5 million Americans (NWHIC); 1% of US population (NIAMS) |
| 212. Campylobacter food poisoning | 0.92% | 1 in 108 | 2.5 million | 2.5 million cases per year (CDC estimate/NIAID); 2 million cases to 8 million cases a year |
| 213. Paralysis | 0.90% | 1 in 111 | 2.4 million | 9 per 1000 - NHIS95 (paralysis of extremeties complete/partial) |
| 214. Vision Impairment | 0.88% | 1 in 113 | 2.4 million | 2.4 million Americans |
| 215. Death | 0.88% | 1 in 113 | 2.4 million | 2,391,399 annual deaths in 1999 (NVHS Sep 2001); annual risk of dying about 0.877% (NVSR 2001) |
| 216. Epilepsy | 0.85% | 1 in 118 | 2.3 million | 2.3 million Americans (CDC) |
| 217. Uveitis | 0.85% | 1 in 118 | 2.3 million | 2,300,000 people suffer uveitis in the US (Research to Prevent Blindness, NISE, NSF) |
| 218. Congenital heart defects | 0.83% | 1 in 120 | 2.3 million | 1 million (NHLBI) |
| 219. Schizophrenia | 0.81% | 1 in 123 | 2.2 million | Approximately 2.2 million American adults (NIMH); estimated 1.3% adults (USSG); more than 2 million Americans |
| 220. Adverse reaction | 0.81% | 1 in 123 | 2.2 million | 2.2 million adverse drug reactions after administration of FDA-approved drugs in USA 1996 (American Medical Association) |
| 221. Deviated Septum | 0.80% | 1 in 124 | 2.2 million | 8 per 1000 - NHIS95 |
| 222. Glaucoma | 0.74% | 1 in 136 | 2 million | 2,000,000 people are visually impaired by glaucoma in the US (Research to Prevent Blindness, NISE, NSF) |
| 223. Vitiligo | 0.74% | 1 in 136 | 2 million | 2 to 5 million people in the USA (1-2% worldwide); 1,059,560 people in the USA 1996 1 |
| 224. Male infertility | 0.74% | 1 in 136 | 2 million | at least 2 million annual cases (based on NWHIC) |
| 225. Female infertility | 0.74% | 1 in 136 | 2 million | at least 2 million annual cases (based on NWHIC) |
| 226. Diverticular Disease | 0.74% | 1 in 136 | 2 million | 2 million people in the USA 1983-87 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 227. Hepatitis C | 0.74% | 1 in 136 | 2 million | estimated 2 to 5 million HCV chronic carriers |
| 228. Alcoholic liver disease | 0.74% | 1 in 136 | 2 million | More than 2 million Americans (NIAAA) |
| 229. Emphysema | 0.74% | 1 in 136 | 2 million | 2 million Americans (NHLBI); 17 per 1000 - NHIS95; 2 million annually |
| 230. Nosocomial infections | 0.74% | 1 in 136 | 2 million | estimated 2 million cases annually or about 10% of American hospital patients (CDC/NNIS 1992) |
| 231. Atrial Fibrillation | 0.74% | 1 in 136 | 2 million | 2 million (NHLBI) |
| 232. Mycoplasma pneumoniae | 0.74% | 1 in 136 | 2 million | estimated 2 million cases annually (DBMD) |
| 233. Polymyalgia rheumatica | 0.70% | 1 in 142 | 1.9 million | 700 per 100,000 people over 50. |
| 234. Chronic tonsilitis | 0.70% | 1 in 142 | 1.9 million | 7 per 1000 - NHIS95 (chronic disease of tonsils or adenoids) |
| 235. Amputation | 0.70% | 1 in 142 | 1.9 million | 7 per 1000 (NHIS95: excludes toes/fingers only) |
| 236. Binge eating disorder | 0.70% | 1 in 142 | 1.9 million | 0.7% to 4% of the general population (NWHIC); 2-5% of adults (NIMH); 2% of adults (NIDDK); 2% adults or 1-2 million adults (NWHIC) |
| 237. Birth Injury | 0.70% | 1 in 142 | 1.9 million | 7 per 1,000 births2. |
| 238. Retina Conditions | 0.66% | 1 in 151 | 1.8 million | 1,800,000 people have severely impaired vision because of retinal disease in the US (Research to Prevent Blindness, NISE, NSF) |
| 239. Hepatitis B | 0.55% | 1 in 181 | 1.5 million | estimated 1.5 million HBV carriers in the U.S. (NWHIC); 417,000 people currently infected (CDC 2001) |
| 240. Fractures | 0.55% | 1 in 181 | 1.5 million | 1.5 million osteoporosis-related fractures |
| 241. Bulimia nervosa | 0.55% | 1 in 181 | 1.5 million | estimated 1.1 to 4.2 percent of females (NIMH); 2-3% of young women (NWHIC) |
| 242. Hashimoto's Thyroiditis | 0.55% | 1 in 182 | 1.5 million | 1,490,371 adults and 205,159 children in the USA 1996 1 |
| 243. Lupus | 0.51% | 1 in 194 | 1.4 million | 1.4 million people in the United States, 1 in 85 (NWHIC) |
| 244. Salmonella food poisoning | 0.51% | 1 in 194 | 1.4 million | estimated 1.4 million cases (CDC estimate/NIAID, many unreported) |
| 245. Wegener's granulomatosis | 0.50% | 1 in 200 | 1.4 million | uncommon |
| 246. HTLV | 0.50% | 1 in 200 | 1.4 million | uncommon |
| 247. HTLV-1 | 0.50% | 1 in 200 | 1.4 million | uncommon |
| 248. Peyronie's disease | 0.50% | 1 in 200 | 1.4 million | 1 per 100 men |
| 249. Sebaceous cyst | 0.50% | 1 in 200 | 1.4 million | 5 per 1000 - NHIS95 |
| 250. Bladder Incontinence (Pregnancy) | 0.49% | 1 in 203 | 1.3 million | 1-in-3 pregnant women approximately |
| 251. Cancer | 0.46% | 1 in 217 | 1.2 million | 1,248,900 annual cases (SEER 2002 estimate) |
| 252. Medical misadventure | 0.42% | 1 in 238 | 1.1 million | 1.14 million total patient safety incidents occurred among 37 million hospitalisations in the US 2000-02 (Patient Safety in American Hospitals, Health Grades 2004) |
| 253. Blindness | 0.40% | 1 in 247 | 1.1 million | 1,100,000 people are legally blind in the US (Research to Prevent Blindness, NISE, NSF) |
| 254. Celiac Disease | 0.40% | 1 in 249 | 1.1 million | 1 in 250 Americans estimated rate; actual diagnosis rate is 1 in 4,700 Americans; 1 in 250 in Italy; 1 in 300 in Ireland; 20,000 diagnosed (Reader's Digest Feb 2004) |
| 255. Arm fracture | 0.39% | 1 in 255 | 1.1 million | 17,819 annual cases in Victoria 1996 of radius/ulna (DHS-VIC) |
| 256. Sports Injuries | 0.38% | 1 in 260 | 1 million | 17,478 annual cases in Victoria 1996 (DHS-VIC) |
| 257. Skin Cancer | 0.37% | 1 in 272 | 1 million | more than 1 million annually (mostly the less dangerous types: basal and squamous) |
| 258. Sjogren's Syndrome | 0.37% | 1 in 272 | 1 million | 1 to 4 million people with Sjogren’s Syndrome (NIAMS) |
| 259. Connective tissue disorders | 0.37% | 1 in 272 | 1 million | estimated 1 million people in USA with heritable connective tissue disorder (NIAMS) |
| 260. Genital warts | 0.37% | 1 in 272 | 1 million | 1 million annual cases in the USA (NIAID) |
| 261. Pelvic Inflammatory Disease | 0.37% | 1 in 272 | 1 million | 1 million women have a PID episode each year (NIAID) |
| 262. Aphasia | 0.37% | 1 in 272 | 1 million | 1 million Americans (NINDS) |
| 263. Kidney stones | 0.37% | 1 in 272 | 1 million | more than 1 million cases (1996, NIDDK) |
| 264. Hemochromatosis | 0.37% | 1 in 272 | 1 million | more than 1 million Americans (CDC); 5 per 1000 in Caucasians (NIDDK); 1-in-200 to 1-in-300 |
| 265. Parkinson's Disease | 0.37% | 1 in 272 | 1 million | 1 million people (unreliable estimate) |
| 266. Dog bite | 0.37% | 1 in 272 | 1 million | 1 million cases (unreliable estimate) |
| 267. Heritable Disorders of Connective Tissue | 0.37% | 1 in 272 | 1 million | estimated 1 million people in USA with heritable connective tissue disorder (NIAMS) |
| 268. Ankle injuries | 0.37% | 1 in 272 | 1 million | 1 million annually (NIAMS); 85% are ankle sprains. |
| 269. Accidental Eye Injury | 0.36% | 1 in 277 | 978,987 | 16,413 annual cases in Victoria 1996 (DHS-VIC) |
| 270. Selective IgA Deficiency | 0.33% | 1 in 300 | 906,666 | 1 in 300 (NIDCD); 1 in 600 (NIAID); 1 in 333 Caucasians. |
| 271. HIV/AIDS | 0.33% | 1 in 302 | 900,000 | 900,000 Americans (NIAID, quarter are unaware) |
| 272. Ankle sprain | 0.31% | 1 in 320 | 850,000 | 850,000 annually (NIAMS) |
| 273. Interstitial cystitis | 0.31% | 1 in 321 | 847,000 | 847,000 in the USA 1988-1994 (Weighted Analysis of 1988-1994 National Health and Nutrition Survey, 2003) |
| 274. Neuralgia | 0.30% | 1 in 333 | 816,000 | 3 per 1000 - NHIS95 (neuralgia or neuritis unspecified) |
| 275. Scoliosis | 0.30% | 1 in 333 | 816,000 | 3-per-1,000 to 5-per-1000 children (NIAMS) |
| 276. Gonorrhea | 0.29% | 1 in 339 | 800,000 | 800,000 cases (CDC estimate/NIAID) |
| 277. Chronic Hepatitis B | 0.28% | 1 in 362 | 750,000 | 750,000 people in the United States (NIAID) |
| 278. Gout | 0.28% | 1 in 363 | 748,000 | 275 per 100,000 people (NIAMS) |
| 279. Spinal fracture | 0.26% | 1 in 388 | 700,000 | more than 700,000 spinal fractures annually in the USA (the number caused by osteoporosis) |
| 280. Poisoning | 0.26% | 1 in 391 | 694,829 | 11,649 annual cases in Victoria 1996 (DHS-VIC) |
| 281. Edentulism | 0.25% | 1 in 400 | 681,706 | 11,429 annual cases in Victoria 1996 (DHS-VIC) |
| 282. Von Hippel-Lindau Disease | 0.25% | 1 in 400 | 680,000 | rare |
| 283. Zollinger-Ellison syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 284. Lichen sclerosis | 0.25% | 1 in 400 | 680,000 | rare |
| 285. Immune Thrombocytopenic Purpura | 0.25% | 1 in 400 | 680,000 | rare. |
| 286. Behcet's Disease | 0.25% | 1 in 400 | 680,000 | rare in the USA; more common in Middle East, Asia, and Japan. |
| 287. Penile candidiasis | 0.25% | 1 in 400 | 680,000 | rare |
| 288. Ascariasis | 0.25% | 1 in 400 | 680,000 | rare |
| 289. Zellweger Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 290. Congenital SMA with arthrogryposis | 0.25% | 1 in 400 | 680,000 | rare |
| 291. Agenesis of the corpus callosum | 0.25% | 1 in 400 | 680,000 | rare |
| 292. Aicardi syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 293. Empty Sella Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 294. Hydranencephaly | 0.25% | 1 in 400 | 680,000 | rare |
| 295. Klippel Feil Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 296. Mobius syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 297. Ataxia Telangiectasia | 0.25% | 1 in 400 | 680,000 | rare |
| 298. Chediak-Higashi Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 299. Machado-Joseph Disease | 0.25% | 1 in 400 | 680,000 | rare |
| 300. Kearns-Sayre Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 301. Alpers Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 302. Agnosia | 0.25% | 1 in 400 | 680,000 | rare |
| 303. Alexander Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 304. Alternating Hemiplegia | 0.25% | 1 in 400 | 680,000 | rare |
| 305. Binswanger's Disease | 0.25% | 1 in 400 | 680,000 | rare |
| 306. Brown-Sequard Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 307. Canavan disease | 0.25% | 1 in 400 | 680,000 | rare |
| 308. Coffin-Lowry syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 309. Fabry's Disease | 0.25% | 1 in 400 | 680,000 | rare |
| 310. Fahr's Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 311. Hallervorden-Spatz disease | 0.25% | 1 in 400 | 680,000 | rare |
| 312. Incontinentia Pigmenti | 0.25% | 1 in 400 | 680,000 | rare |
| 313. Joubert Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 314. Krabbé Disease | 0.25% | 1 in 400 | 680,000 | rare |
| 315. Landau-Kleffner Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 316. Microcephaly | 0.25% | 1 in 400 | 680,000 | rare |
| 317. Miller Fisher Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 318. Moyamoya Disease | 0.25% | 1 in 400 | 680,000 | rare |
| 319. Parry Romberg Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 320. Pelizaeus-Merzbacher Disease | 0.25% | 1 in 400 | 680,000 | rare |
| 321. Primary Lateral Sclerosis | 0.25% | 1 in 400 | 680,000 | rare |
| 322. Progressive Supranuclear Palsy | 0.25% | 1 in 400 | 680,000 | rare |
| 323. Rasmussen's Encephalitis | 0.25% | 1 in 400 | 680,000 | rare |
| 324. Sandhoff Disease | 0.25% | 1 in 400 | 680,000 | rare |
| 325. Schilder's Disease | 0.25% | 1 in 400 | 680,000 | rare |
| 326. Septo-Optic Dysplasia | 0.25% | 1 in 400 | 680,000 | rare |
| 327. Soto's Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 328. Stiff-Person Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 329. Subacute Sclerosing Panencephalitis | 0.25% | 1 in 400 | 680,000 | rare - because of the rarity of measles due to vaccination programs. |
| 330. Williams Syndrome | 0.25% | 1 in 400 | 680,000 | rare |
| 331. Ménétrier's disease | 0.25% | 1 in 400 | 680,000 | rare |
| 332. Acute Appendicitis | 0.25% | 1 in 400 | 680,000 | 25 per 10,000 (age 10-17), 1-2 per per 10,000 (under 4) |
| 333. Goodpasture syndrome | 0.25% | 1 in 400 | 680,000 | rare. |
| 334. Encephaloceles | 0.25% | 1 in 400 | 680,000 | rare |
| 335. Ramsay Hunt Syndrome Type 2 | 0.25% | 1 in 400 | 680,000 | rare |
| 336. Mastocytosis | 0.25% | 1 in 400 | 680,000 | rare |
| 337. Cutaneous mastocytosis | 0.25% | 1 in 400 | 680,000 | rare |
| 338. Restrictive cardiomyopathy | 0.25% | 1 in 400 | 680,000 | rare |
| 339. Pulmonary embolism | 0.24% | 1 in 418 | 650,000 | approximately 650,000 cases annually in the USA |
| 340. Bacterial vaginosis | 0.24% | 1 in 424 | 640,000 | 16% of pregnant women (DSTD) |
| 341. Gall bladder conditions | 0.23% | 1 in 438 | 620,031 | 10,395 annual cases of gallbladder and bile duct disease in Victoria 1996 (DHS-VIC) |
| 342. Caesarian Section | 0.22% | 1 in 453 | 600,000 | more than 600,000 annually |
| 343. Polycystic kidney disease | 0.22% | 1 in 453 | 600,000 | 600,000 Americans |
| 344. Hysterectomy | 0.22% | 1 in 461 | 590,000 | 590,000 annually |
| 345. Inflammatory bowel disease | 0.20% | 1 in 500 | 544,000 | 1 in 500 (NIAID); 300,000 people to 500,000 people NIDDK |
| 346. Klinefelter syndrome | 0.20% | 1 in 500 | 544,000 | 1-in-500 to 1-in-1000 male births (NIDCD) |
| 347. Congenital hip dislocation | 0.20% | 1 in 500 | 544,000 | about 2 per 1000 births; up to 4 per 1000 |
| 348. Sickle Cell Anemia | 0.20% | 1 in 500 | 544,000 | 72,000 people in USA (NHLBI); 2 million carriers (USA); 1 in 12 African American carriers |
| 349. Autism | 0.20% | 1 in 500 | 544,000 | 1 in 500 to 1 in 2,500 (NIMH); 1-in-1000 to 2-in-1000, depending on diagnostic criteria |
| 350. Nonaffective Psychosis | 0.20% | 1 in 500 | 544,000 | estimated 0.2% adults (USSG) |
| 351. Somatization Disorder | 0.20% | 1 in 500 | 544,000 | estimated 0.2% adults (USSG) |
| 352. Postpartum psychosis | 0.20% | 1 in 500 | 544,000 | 1 in 500 to 1,000 new mothers |
| 353. Cerebral Palsy | 0.20% | 1 in 500 | 544,000 | 2 to 2.5 per 1,000 births (FMC) |
| 354. Traumatic Brain Injury | 0.20% | 1 in 500 | 544,000 | 0.2% of population has an acquired brain injury in Australia 1998 (Australia’s Health 2004, AIHW) |
| 355. Temporal arteritis | 0.20% | 1 in 500 | 544,000 | 200 per 100,000 people over 50. |
| 356. Intussusception | 0.20% | 1 in 500 | 544,000 | about 2 per 1000 cases in infants |
| 357. Hypertrophic cardiomyopathy | 0.20% | 1 in 500 | 544,000 | 0.2 percent of the U.S. population |
| 358. Sudden Infant Death Syndrome | 0.20% | 1 in 500 | 544,000 | 2 per 1,000 |
| 359. Autosomal dominant polycystic kidney disease | 0.20% | 1 in 503 | 540,000 | 540,000 Americans approximately (90% of PKD) |
| 360. Hand fracture | 0.20% | 1 in 507 | 536,287 | 8,991 annual cases in Victoria 1996 (DHS-VIC) |
| 361. Crohn's disease | 0.18% | 1 in 544 | 500,000 | 500,000 Americans |
| 362. Chronic Fatigue Syndrome | 0.18% | 1 in 544 | 500,000 | 500,000 Americans (CDC/NIAID) |
| 363. Shingles | 0.18% | 1 in 544 | 500,000 | 500,000 cases (NIAID) |
| 364. Inguinal hernia | 0.18% | 1 in 544 | 500,000 | 500,000 cases (NIDDK) |
| 365. Pneumococcal pneumonia | 0.18% | 1 in 544 | 500,000 | 500,000 cases annually (NIAID) |
| 366. Bedsores | 0.17% | 1 in 573 | 474,692 | 474,692 new cases of decubitus ulcer occurred in the US 2000-2002 (Patient Safety in American Hospitals, Health Grades 2004) |
| 367. Viral Hepatitis | 0.17% | 1 in 601 | 452,000 | about 452,000 annual cases based on incidence of HepA, HepB, HepC, and HepD (NIDDK 1990-1992) |
| 368. Chronic Nonulcer dyspepsia | 0.16% | 1 in 612 | 444,000 | 444,000 new cases (1975/NIDDK) |
| 369. Premature Birth | 0.16% | 1 in 618 | 440,000 | 440,000 cases (unreliable estimate) |
| 370. Benign Prostate Hyperplasia | 0.16% | 1 in 627 | 433,216 | 7,263 annual cases in Victoria 1996 (DHS-VIC) |
| 371. Liver conditions | 0.15% | 1 in 679 | 400,000 | 400,000 people in the USA 1976-80 for "chronic liver disease and cirrhosis" (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 372. Postpartum depression | 0.15% | 1 in 679 | 400,000 | 10% of pregnancies. |
| 373. Chronic liver disease | 0.15% | 1 in 679 | 400,000 | 400,000 people |
| 374. Cirrhosis of the liver | 0.15% | 1 in 679 | 400,000 | 400,000 people in the USA 1976-80 for "chronic liver disease and cirrhosis" (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 375. Ocular Herpes | 0.15% | 1 in 679 | 400,000 | 400,000 Americans have had some form |
| 376. Pernicious anemia | 0.15% | 1 in 680 | 399,454 | 399,455 people in the USA 1996 1 |
| 377. End-stage renal disease | 0.14% | 1 in 693 | 392,022 | 392,023 people in the USA 2001 (United States Renal Data System 2003 Annual Data Report, 2003) |
| 378. Multiple Sclerosis | 0.14% | 1 in 700 | 388,571 | 1-in-700 (NIAID) |
| 379. Triple-X syndrome | 0.14% | 1 in 700 | 388,571 | 1-in-700 approximately. |
| 380. Cleft palate | 0.14% | 1 in 700 | 388,571 | about 1 in 700 births |
| 381. Dementia | 0.14% | 1 in 738 | 368,320 | 6,175 annual cases in Victora 1996 (DHS-VIC) |
| 382. Intestinal obstruction | 0.13% | 1 in 746 | 364,563 | 6,112 annual cases in Victoria 1996 (DHS-VIC) |
| 383. Burns | 0.13% | 1 in 754 | 360,507 | 6,044 annual cases in Victora 1996 for fires/burns/scalds (DHS-VIC) |
| 384. Ankylosing Spondylitis | 0.13% | 1 in 775 | 350,879 | 129 of every 100,000 people in the US (Mayo Clinic) |
| 385. Type 1 diabetes | 0.12% | 1 in 800 | 340,000 | 1-in-800 (NIAID) |
| 386. Down Syndrome | 0.12% | 1 in 800 | 340,000 | 1-in-800 overall births |
| 387. Genital system cancer | 0.12% | 1 in 841 | 323,210 | 323,210 new cases for genital system cancer in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 388. Neural tube defect | 0.12% | 1 in 864 | 314,703 | 11.57 per 10,000 births with neural tube defects in the UK 2002 (University of Ulster, 2003) |
| 389. Shoulder Fracture | 0.12% | 1 in 867 | 313,624 | 5,258 annual cases in Victoria 1996 of clavicle/scapula/humerus (DHS-VIC) |
| 390. Scleroderma | 0.11% | 1 in 906 | 300,000 | estimated 300,000 Americans (NWHIC) |
| 391. Hip fracture | 0.11% | 1 in 906 | 300,000 | more than 300,000 hip fractures annually (the number due to osteoporosis) |
| 392. Machinery accidents | 0.11% | 1 in 942 | 288,453 | 4,836 annual cases in Victoria 1996 (DHS-VIC) |
| 393. Kidney Dialysis | 0.11% | 1 in 946 | 287,493 | 287,494 people in the USA 2001 (United States Renal Data System 2003 Annual Data Report, 2003) |
| 394. Natural accidents | 0.10% | 1 in 958 | 283,800 | 4,758 annual cases in Victoria 1996 of natural/environmental factors (DHS-VIC) |
| 395. Anorexia Nervosa | 0.10% | 1 in 1,000 | 272,000 | estimated 0.1% adults (USSG); estimated 0.5 to 3.7 percent females (NIMH); 1% of adolescent girls (NWHIC) |
| 396. Clubfoot | 0.10% | 1 in 1,000 | 272,000 | about 1 per 1,000 births2. |
| 397. Ankle fracture | 0.10% | 1 in 1,048 | 259,524 | 4,351 annual cases in Victoria 1996 (DHS-VIC) |
| 398. Face fracture | 0.09% | 1 in 1,063 | 255,826 | 4,289 annual cases in Victoria 1996 (DHS-VIC) |
| 399. Digestive system cancer | 0.09% | 1 in 1,063 | 255,640 | 255,640 new cases for digestive system cancer in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 400. Wrist fracture | 0.09% | 1 in 1,088 | 250,000 | at least 250,000 wrist fractures (the number caused by osteoporosis annually in the USA) |
| 401. Fractured femur | 0.09% | 1 in 1,155 | 235,486 | 3,948 annual cases in Victoria 1996 (DHS-VIC) |
| 402. Foot fracture | 0.08% | 1 in 1,240 | 219,262 | 3,676 annual cases in Victoria 1996 (DHS-VIC) |
| 403. Fractured Lower Leg | 0.08% | 1 in 1,304 | 208,466 | 3,495 annual cases in Victoria 1996 (DHS-VIC) |
| 404. Breast Cancer | 0.08% | 1 in 1,326 | 205,000 | 205,000 annual cases (SEER 2002 estimate); 180,000 annual cases (NCI); only about 1,000 men |
| 405. Narcolepsy | 0.07% | 1 in 1,359 | 200,000 | 200,000 Americans (NHLBI estimate); 50,000 diagnosed. |
| 406. Prostate Cancer | 0.07% | 1 in 1,439 | 189,000 | 189,000 annual cases in USA (SEER 2002 estimate); 168,665 new cases (NIDDK) |
| 407. Respiratory system cancer | 0.07% | 1 in 1,458 | 186,550 | 186,550 new cases for respiratory system cancer in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 408. Norwalk-like viruses | 0.07% | 1 in 1,502 | 181,000 | estimated 181,000 cases annually in USA (CDC-OC) |
| 409. Aortic aneurysm | 0.07% | 1 in 1,537 | 176,913 | 2,966 annual cases in Victoria 1996 (DHS-VIC) |
| 410. Hydrocephalus | 0.06% | 1 in 1,547 | 175,711 | 6.46 per 10,000 births in the UK 2002 for hydrocephaly (University of Ulster, 2003) |
| 411. Lung cancer | 0.06% | 1 in 1,605 | 169,400 | 169,400 annual cases (SEER 2002 estimate: lung and bronchus cancers) |
| 412. Adult respiratory distress syndrome | 0.06% | 1 in 1,813 | 150,000 | 150,000 adults (NHLBI) |
| 413. Colorectal cancer | 0.05% | 1 in 1,834 | 148,300 | 148,300 annual cases = 107,300 annual cases of colon cancer and 41,000 annual cases of rectum cancer(SEER 2002 estimate) |
| 414. Preeclampsia | 0.05% | 1 in 1,858 | 146,320 | 146,320 cases (1998/NHLBI); about 5% of pregnancies. |
| 415. Méničre's disease | 0.05% | 1 in 1,973 | 137,847 | about 10,000 people in Australia |
| 416. Autoimmune Lymphoproliferative Syndrome | 0.05% | 1 in 2,000 | 136,000 | very rare; NIAID mentions 58 individuals |
| 417. Neonatal lupus | 0.05% | 1 in 2,000 | 136,000 | very rare |
| 418. Jacobs syndrome | 0.05% | 1 in 2,000 | 136,000 | 1-in-2000 approximately. |
| 419. Androgen Insensitivity Syndrome | 0.05% | 1 in 2,000 | 136,000 | very rare |
| 420. Porencephaly | 0.05% | 1 in 2,000 | 136,000 | extremely rare |
| 421. Schizencephaly | 0.05% | 1 in 2,000 | 136,000 | extremely rare |
| 422. Keratoconus | 0.05% | 1 in 2,000 | 136,000 | 1-in-2000 Americans |
| 423. Gestational diabetes | 0.05% | 1 in 2,014 | 135,000 | 135,000 pregnant women get the condition every year; 3-5% of pregnant women. |
| 424. Chickenpox | 0.04% | 1 in 2,254 | 120,624 | 120,624 annually (1995); 46,016 annual cases notified in USA 1999 (MMWR 1999); 199.14 per 100,000 in Canada 20003 |
| 425. Hip Replacement | 0.04% | 1 in 2,266 | 120,000 | 120,000 annually (NIAMS); 120,000 annual hip replacement operations in the USA. |
| 426. Whiplash | 0.04% | 1 in 2,266 | 120,000 | 120,000 annually |
| 427. Carbon monoxide poisoning | 0.04% | 1 in 2,400 | 113,333 | 25,000 annual cases of home exposure in the UK |
| 428. Lyme disease | 0.04% | 1 in 2,719 | 100,000 | estimated 100,000 cases annually (NIAID/USA) |
| 429. Hyperparathyroidism | 0.04% | 1 in 2,719 | 100,000 | 100,000 cases per year in the USA |
| 430. Retinitis Pigmentosa | 0.04% | 1 in 2,719 | 100,000 | 100,000 people have retinitis pigmentosa which can cause retinal deterioration and blindness in the US (Research to Prevent Blindness, NISE, NSF) |
| 431. Urinary system cancer | 0.04% | 1 in 2,764 | 98,400 | 98,400 new cases for urinary system cancer in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 432. Septicemia | 0.04% | 1 in 2,767 | 98,300 | 1,648 annual cases in Victora 1996 (DHS-VIC) |
| 433. Accidental death | 0.03% | 1 in 2,906 | 93,591 | 93,592 annual cases in 2000 (CDC); 97,860 annual cases in 1999 (NVSR Sep 2001) |
| 434. Edwards Syndrome | 0.03% | 1 in 3,000 | 90,666 | 1-in-3000 approximately. |
| 435. Velocardiofacial syndrome | 0.03% | 1 in 3,000 | 90,666 | 1-in-3000 approximately. |
| 436. Fragile-X Syndrome | 0.03% | 1 in 3,000 | 90,666 | about 1 in 1500 males4. |
| 437. Familial emphysema | 0.03% | 1 in 3,000 | 90,666 | 70,000 Americans |
| 438. Neurofibromatosis | 0.03% | 1 in 3,000 | 90,666 | about 1 in 30004. |
| 439. Suffocation | 0.03% | 1 in 3,285 | 82,790 | 1,388 annual cases in Victoria 1996 of suffocation and foreign bodies (DHS-VIC) |
| 440. Vagina cancer | 0.03% | 1 in 3,333 | 81,600 | 3 in 10,000 for DES-related cases of vaginal cancer. |
| 441. Diethylstilbestrol | 0.03% | 1 in 3,333 | 81,600 | 3 per 10,000 with a risk of vaginal cancer; probably higher if include other complications of DES |
| 442. Acute Pancreatitis | 0.03% | 1 in 3,400 | 80,000 | 80,000 cases occur in the USA (NIDDK); 17 per 100,000 new cases |
| 443. Vertebral fracture | 0.03% | 1 in 3,619 | 75,155 | 1,260 annual cases in Victoria 1996 (DHS-VIC) |
| 444. Heroin dependence | 0.03% | 1 in 3,692 | 73,664 | 1,235 annual cases in Victoria 1996 (DHS-VIC) |
| 445. Escherichia coli O157:H7 | 0.03% | 1 in 3,726 | 73,000 | estimated 73,000 annual cases of infection in USA (DBMD) |
| 446. Cannabis dependence | 0.03% | 1 in 3,759 | 72,351 | 1,213 annual cases in Victoria 1996 (DHS-VIC) |
| 447. Sedative dependence | 0.03% | 1 in 3,759 | 72,351 | 1,213 annual cases in Victoria 1996 (DHS-VIC) |
| 448. Syphilis | 0.03% | 1 in 3,885 | 70,000 | 70,000 cases (NIAID; CDC 2001) |
| 449. Ectopic pregnancy | 0.03% | 1 in 3,885 | 70,000 | 70,000 cases annually; about 1 in 250 pregnancies. |
| 450. Hepatitis D | 0.03% | 1 in 3,885 | 70,000 | 70,000 new cases in the USA 1990 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 451. Congenital hypothyroidism | 0.03% | 1 in 4,000 | 68,000 | about 1 in 4000 babies |
| 452. Diabetic Retinopathy | 0.02% | 1 in 4,184 | 65,000 | 65,000 diabetics develop proliferative retinopathy, the most sight-threatening stage in the US (Research to Prevent Blindness, NISE, NSF) |
| 453. Holoprosencephaly | 0.02% | 1 in 4,201 | 64,736 | 2.38 per 10,000 births in the UK 2002 for arhinencephaly/holprosencephaly (University of Ulster, 2003) |
| 454. Multiple Myeloma | 0.02% | 1 in 4,317 | 63,000 | about 63,000 people affected by multiple myeloma ("Orphan Products: Hope for People With Rare Diseases", By Carol Rados, FDA Consumer magazine, November-December 2003 Issue) |
| 455. Primary Glomerulonephritis | 0.02% | 1 in 4,428 | 61,422 | 61,423 people with Primary Glomerulonephritis in the USA 1996 1 |
| 456. IgA nephropathy | 0.02% | 1 in 4,428 | 61,422 | 61,423 people in the USA 1996 1 |
| 457. Lymphoma | 0.02% | 1 in 4,466 | 60,900 | 60,900 annual cases in USA (SEER 2002 estimate) |
| 458. Pelvic fracture | 0.02% | 1 in 4,475 | 60,780 | 1,019 annual cases in Victoria 1996 (DHS-VIC) |
| 459. Bladder Cancer | 0.02% | 1 in 4,814 | 56,500 | 56,500 annual cases in USA (SEER 2002 estimate) |
| 460. Patau syndrome | 0.02% | 1 in 5,000 | 54,400 | 1-in-5000 approximately. |
| 461. Turner Syndrome | 0.02% | 1 in 5,000 | 54,400 | 1-in-5000 |
| 462. Sarcoidosis | 0.02% | 1 in 5,000 | 54,400 | 20 per 100,000 overall; 5 in 100,000 white people; 40 out of 100,000 black people; Scandinavia 64 out of 100,000 people |
| 463. Aortic coarctation | 0.02% | 1 in 5,000 | 54,400 | 1 in 5000 babies |
| 464. Marfan syndrome | 0.02% | 1 in 5,000 | 54,400 | 1 in 5,000 people in the USA |
| 465. Ehlers-Danlos syndrome | 0.02% | 1 in 5,000 | 54,400 | 1 in 5,000 to 10,000 (Ehler's Danlos National Foundation) |
| 466. Non-Hodgkin's Lymphoma | 0.02% | 1 in 5,046 | 53,900 | 53,900 annual cases in USA (SEER 2002 estimate) |
| 467. Melanoma | 0.02% | 1 in 5,074 | 53,600 | 53,600 annual cases (SEER 2002 estimate: skin melanomas) |
| 468. Cardiomyopathy | 0.02% | 1 in 5,439 | 50,000 | 50,000 Americans (NHLBI) |
| 469. Pancreatitis | 0.02% | 1 in 5,882 | 46,240 | 17 new cases per 100,000 in the USA 1976-88 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 470. Duchenne Muscular Dystrophy | 0.02% | 1 in 6,000 | 45,333 | about 1 in 3000 males4. |
| 471. Giardia | 0.02% | 1 in 6,138 | 44,308 | 16.29 per 100,000 in Canada 20003 |
| 472. Skull fracture | 0.02% | 1 in 6,413 | 42,409 | 711 annual cases in Victoria 1996 (DHS-VIC) |
| 473. Diabetes Insipidus | 0.01% | 1 in 6,666 | 40,800 | less than 15 per 100,000 hospitalized patients |
| 474. Coccidioidomycosis | 0.01% | 1 in 6,666 | 40,800 | 15 cases per 100,000 population in Arizona in 1995 (DBMD) |
| 475. Rectal cancer | 0.01% | 1 in 6,704 | 40,569 | 40,570 new cases for rectum cancer in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 476. Bell's Palsy | 0.01% | 1 in 6,800 | 40,000 | 40,000 annual cases in Americans |
| 477. Neonatal Respiratory Distress Syndrome | 0.01% | 1 in 6,800 | 40,000 | 40,000 infants and 150,000 adults with adult RDS (NHLBI) |
| 478. Endometrial Cancer | 0.01% | 1 in 6,921 | 39,300 | 39,300 annual cases in USA (SEER 2002 estimate) |
| 479. Prolactinoma | 0.01% | 1 in 7,142 | 38,080 | less than 14 per 100,000 (the rate for pituitary tumors) |
| 480. Pituitary Cancer | 0.01% | 1 in 7,142 | 38,080 | 14 per 100,000 people (NIDDK) |
| 481. Hepatitis A | 0.01% | 1 in 8,500 | 32,000 | 32,000 new cases in the USA 1992 (Digestive diseases in the United States: Epidemiology and Impact – NIH Publication No. 94-1447, NIDDK, 1994) |
| 482. Kidney Cancer | 0.01% | 1 in 8,553 | 31,800 | 31,800 annual cases in USA (SEER 2002 estimate); more than 28,000 cases annually in the United States |
| 483. Leukemia | 0.01% | 1 in 8,831 | 30,800 | 30,800 annual cases in USA (SEER 2002 estimate) including 10,800 lymphocytic, 15,000 myeloid and 5,000 other leukemias; about 29,000 cases annually (NCI); nearly 27,000 adults and more than 2,000 children annually. |
| 484. Pancreatic cancer | 0.01% | 1 in 8,976 | 30,300 | 30,300 annual cases (SEER 2002 estimate) |
| 485. Amyotrophic lateral sclerosis | 0.01% | 1 in 9,066 | 30,000 | 30,000 cases of ALS in America (Robert Packard Research Center at John Hopkins Hospital) |
| 486. Cystic Fibrosis | 0.01% | 1 in 9,066 | 30,000 | 30,000 Americans (NIDDK) |
| 487. Suicide | 0.01% | 1 in 9,315 | 29,200 | 29,199 annual cases of actual suicide in 1999 USA (NVHS Sep 2001) |
| 488. Oral cancer | 0.01% | 1 in 9,411 | 28,900 | 28,900 annual cases (SEER 2002 estimate) |
| 489. Firearm Injury | 0.01% | 1 in 9,420 | 28,873 | 28,874 annual cases causing death in 1999 USA (NVSR Sep 2001) |
| 490. Tuberous sclerosis | 0.01% | 1 in 10,000 | 27,200 | less than 1 in 10,000 |
| 491. Autoimmune Thrombocytopenia | 0.01% | 1 in 10,000 | 27,200 | less than 10 per 100,000 cases and 1-4 per 100,000 in children1 |
| 492. Phenylketonuria | 0.01% | 1 in 10,000 | 27,200 | 1 of every 10,000 infants in the United States (NIDCD) |
| 493. Rett's syndrome | 0.01% | 1 in 10,000 | 27,200 | 1 in 10,000-15,000 live female births |
| 494. Osteogenesis imperfecta | 0.01% | 1 in 10,000 | 27,200 | about 1 in 10,0004. |
| 495. Endocrine system cancer | 0.01% | 1 in 10,658 | 25,520 | 25,520 new cases for endocrine system cancer in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 496. E-coli food poisoning | 0.01% | 1 in 10,879 | 25,000 | 25,000 cases per year estimated |
| 497. Meningitis | 0.01% | 1 in 10,879 | 25,000 | approximately 25,000 cases of bacterial meningitis annually in USA; 206 annual cases in Victoria 1996 (DHS-VIC) |
| 498. Fetal alcohol syndrome | 0.01% | 1 in 11,111 | 24,479 | 0.9 per 10,000 births (Caucasians); Asians 0.3, Hispanics 0.8, African Americans 6.0, and Native Americans 29.9 (NWHIC). |
| 499. Amputated thumb | 0.01% | 1 in 11,573 | 23,500 | 394 annual cases in Victoria 1996 (DHS-VIC) |
| 500. Ovarian Cancer | 0.01% | 1 in 11,673 | 23,300 | 23,300 annual cases in USA (SEER 2002 estimate); about 1 in 57 women in the United States (NCI) |
| 501. Invasive candidiasis | 0.01% | 1 in 12,500 | 21,760 | 8 per 100,000 for candidemia (DBMD) |
| 502. Stomach cancer | 0.01% | 1 in 12,592 | 21,600 | 21,600 annual cases (SEER 2002 estimate); about 24,000 annual cases in the United States (NCI) |
| 503. Amputated finger | 0.01% | 1 in 13,066 | 20,816 | 349 annual cases in Victoria 1996 (DHS-VIC) |
| 504. Thyroid cancer | 0.01% | 1 in 13,140 | 20,700 | 20,700 annual cases in USA (SEER 2002 estimate); 19,500 annual cases in the USA (NCI); 14,900 women and 4,600 men annually (NCI). |
| 505. Uterine Cancer | 0.01% | 1 in 13,333 | 20,400 | 4,500 women in the UK 2001 (National Statistics, UK Government Census, 2001) |
| 506. Ross River virus | 0.01% | 1 in 13,513 | 20,128 | 7.4 new cases per 100,000 population of Ross River Virus infection was notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW) |
| 507. Hemophilia | 0.01% | 1 in 13,600 | 20,000 | 20,000 people in the United States (NHLBI) |
| 508. Placenta previa | 0.01% | 1 in 13,600 | 20,000 | 1 in 200 pregnancies (FMC) |
| 509. Transplants | 0.01% | 1 in 14,315 | 19,000 | more than 19,000 transplants annually in USA (NIAID) |
| 510. Group B Streptococcal Infections | 0.01% | 1 in 14,492 | 18,767 | 6.9 cases per 100,000 (DBMD) |
| 511. Tuberculosis | 0.01% | 1 in 14,814 | 18,360 | 18,361 cases annually in the USA (1998); 8 million people worldwide develop active TB and 3 million die; 17,531 annual cases notified in USA 1999 (MMWR 1999); 5.50 per 100,000 in Canada 20003 |
| 512. Rabies | 0.01% | 1 in 15,111 | 18,000 | 18,000 cases (of rabies shots rather than actual rabies) |
| 513. Shigellosis | 0.01% | 1 in 15,524 | 17,521 | 17,521 annual cases of shigellosis notified in USA 1999 (MMWR 1999) |
| 514. Brain cancer | 0.01% | 1 in 16,000 | 17,000 | 17,000 annual cases in USA (SEER 2002 estimate: brain and other nervous system) |
| 515. Homicide | 0.01% | 1 in 16,105 | 16,889 | 16,889 annual cases in 1999 including 10,828 for firearms (NVSR Sep 2001) |
| 516. Liver cancer | 0.01% | 1 in 16,385 | 16,600 | 16,600 annual cases (SEER 2002 estimate) |
| 517. Spina bifida | 0.01% | 1 in 16,666 | 16,320 | 6 per 100,000 births |
| 518. Usher Syndrome | 0.01% | 1 in 17,000 | 16,000 | 16,000 Americans |
| 519. Kidney transplant | 0.01% | 1 in 17,741 | 15,331 | 15,331 procedures in the USA 2001 (United States Renal Data System 2003 Annual Data Report, 2003) |
| 520. Myelodysplastic syndromes | 0.01% | 1 in 19,428 | 14,000 | 14,000 people are diagnosed with myelodysplastic syndrome each year in the US (American Cancer Society, Medical News Today) |
| 521. Myasthenia Gravis | 0.00% | 1 in 20,000 | 13,600 | about 5 per 100,000 to 14 per 100,000 (NWHIC) |
| 522. Dermatomyositis | 0.00% | 1 in 20,205 | 13,461 | 13,462 people with polymyositis/dermatomyositis in the USA 1996 1 |
| 523. Cervical Cancer | 0.00% | 1 in 20,923 | 13,000 | 13,000 annual cases in USA (SEER 2002 estimate) |
| 524. Barmah Forest virus | 0.00% | 1 in 21,739 | 12,512 | 4.6 new cases per 100,000 population of Barmah Forest Virus infection was notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW) |
| 525. Larynx Cancer | 0.00% | 1 in 22,666 | 12,000 | 12,000 annual cases in the United States (NCI); 8,900 annual cases (SEER 2002 estimate) |
| 526. Acute myeloid leukemia | 0.00% | 1 in 22,818 | 11,919 | 11,920 new cases for Acute Myeloid Leukemia in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 527. Rheumatic heart disease | 0.00% | 1 in 23,505 | 11,571 | 194 annual cases in Victoria 1996 (DHS-VIC) |
| 528. Acromegaly | 0.00% | 1 in 25,000 | 10,880 | 40-60 per million affected people at any time |
| 529. Q fever | 0.00% | 1 in 25,641 | 10,608 | 3.9 new cases per 100,000 population of Q Fever were notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW) |
| 530. Mouth cancer | 0.00% | 1 in 26,984 | 10,080 | 10,080 new cases for mouth cancer in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 531. Toxocariasis | 0.00% | 1 in 27,200 | 10,000 | estimated 10,000 annual cases in USA (DPD) |
| 532. Avascular necrosis | 0.00% | 1 in 27,200 | 10,000 | 10,000 to 20,000 annual cases (NIAMS) |
| 533. Primary biliary cirrhosis | 0.00% | 1 in 29,462 | 9,231 | 9,232 people in the USA 1996 1 |
| 534. Viral meningitis | 0.00% | 1 in 30,452 | 8,932 | 8,932 new cases in America 1995 (Meningitis Foundation of America, CDC, 1994) |
| 535. Group A Streptococcal Infections | 0.00% | 1 in 31,249 | 8,704 | 3.2 cases per 100,000 (DBMD) |
| 536. Soft Tissue Sarcoma | 0.00% | 1 in 32,771 | 8,300 | 8,300 annual cases (SEER 2002 estimate) |
| 537. Pharynx cancer | 0.00% | 1 in 32,969 | 8,250 | 8,250 new cases for pharynx cancer in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 538. Chronic lymphocytic leukemia | 0.00% | 1 in 33,211 | 8,190 | 8,190 new cases for Chronic Lymphocytic Leukemia in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 539. Colonic volvulus | 0.00% | 1 in 33,333 | 8,160 | 3 per 100,000 persons per year |
| 540. Multiple endocrine neoplasia type 1 | 0.00% | 1 in 33,333 | 8,160 | 3 per 100,000 up to 20 per 100,000 (NIDDK) |
| 541. Testicular Cancer | 0.00% | 1 in 36,266 | 7,500 | 7,500 annual cases in USA (SEER 2002 estimate) |
| 542. Whooping Cough | 0.00% | 1 in 36,731 | 7,405 | 7,405 cases annually in USA (1998); under-diagnosis of cases in adults means the real prevalence may be much higher |
| 543. Tongue Cancer | 0.00% | 1 in 37,158 | 7,320 | 7,320 new cases for tongue cancer in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 544. Gall Bladder Cancer | 0.00% | 1 in 38,309 | 7,100 | 7,100 annual cases (SEER 2002 estimate: gallbladder and other biliary) |
| 545. Hodgkin's Disease | 0.00% | 1 in 38,857 | 7,000 | 7,000 annual cases in USA (SEER 2002 estimate); less than 1 percent of all cases of cancer |
| 546. Infant Cytomegalic virus | 0.00% | 1 in 45,333 | 6,000 | 6,000 babies |
| 547. Motor neuron diseases | 0.00% | 1 in 49,566 | 5,487 | 92 annual cases in Victoria 1996 (DHS-VIC) |
| 548. Small Intestine Cancer | 0.00% | 1 in 51,320 | 5,300 | 5,300 annual cases (SEER 2002 estimate) |
| 549. Bronchopulmonary dysplasia | 0.00% | 1 in 54,400 | 5,000 | 5,000 to 10,000 new cases |
| 550. Brainerd diarrhea | 0.00% | 1 in 54,400 | 5,000 | estimated 5,000-8,000 patients (DBMD) |
| 551. Reiter’s syndrome | 0.00% | 1 in 57,142 | 4,760 | 3.5 per 100,000 men under age 50 get Reiter’s syndrome each year |
| 552. Autoimmune uveitis | 0.00% | 1 in 58,658 | 4,637 | 4,637 people in the USA 1996 1 |
| 553. Chronic myeloid leukemia | 0.00% | 1 in 59,130 | 4,600 | 4,600 new cases for Chronic Myeloid Leukemia in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 554. Corneal Dystrophies | 0.00% | 1 in 64,761 | 4,200 | 4,200 people have reduced vision because of corneal dystrophies in the US (Research to Prevent Blindness, NISE, NSF) |
| 555. Anencephaly | 0.00% | 1 in 68,000 | 4,000 | less than 4,000 cases (the rate for spina bifida and anencephaly, NWHIC) |
| 556. Anal Cancer | 0.00% | 1 in 69,743 | 3,900 | 3,900 annual cases (SEER 2002 estimate) |
| 557. Acute lymphocytic leukemia | 0.00% | 1 in 71,018 | 3,830 | 3,830 new cases for Acute Lymphocytic Leukemia in the US 2004 (Cancer Facts and Figures, American Cancer Society, 2004) |
| 558. Vulva cancer | 0.00% | 1 in 71,578 | 3,800 | 3,800 annual cases in USA (SEER 2002 estimate) |
| 559. Autoimmune Hemolytic Anemia | 0.00% | 1 in 80,000 | 3,400 | 1 per 80,000 cases to 2.6 per 100,000 (as reported in Rose and Mackay 19985) |
| 560. Amyloidosis | 0.00% | 1 in 90,666 | 3,000 | less than 3,000 people in the US (Mayo Clinic) |
| 561. Addison's Disease | 0.00% | 1 in 100,000 | 2,720 | 1 in 100,000; 13,335 people in the USA 1996 1 |
| 562. Guillain-Barre Syndrome | 0.00% | 1 in 100,000 | 2,720 | about 1 in 100,000 (NWHIC) |
| 563. Mycobacterium avium Complex | 0.00% | 1 in 100,000 | 2,720 | 1 per 100,000 annually (DBMD) |
| 564. Aspergillosis | 0.00% | 1 in 100,000 | 2,720 | 1-2 per 100,000 per year (DBMD) |
| 565. X-Linked Agammaglobulinemia | 0.00% | 1 in 100,000 | 2,720 | 1-in-100,000 |
| 566. Yersiniosis | 0.00% | 1 in 100,000 | 2,720 | approx 1 per 100,000 annually (DBMD); 19 cases in NJ 1998 (NJ DHSS) |
| 567. Pneumococcal meningitis | 0.00% | 1 in 100,000 | 2,720 | about 1 to 2 per 100,000 in the USA |
| 568. Cushing's syndrome | 0.00% | 1 in 100,000 | 2,720 | 2-5 per million (NIDCD); 10 per million; 10-15 per million |
| 569. Drowning | 0.00% | 1 in 100,000 | 2,720 | 1 per 100,000 population drowns in Australia 2002 (Australia’s Health 2004, AIHW) |
| 570. Blastomycosis | 0.00% | 1 in 100,000 | 2,720 | 1-2 cases per 100,000 (DBMD) |
| 571. Infant Death | 0.00% | 1 in 102,719 | 2,648 | 2,648 annual cases (NVSR Sep 2001); 7.1 per 1,000 infant deaths (per births) in USA 1999 (NVSR Sep 2001) |
| 572. Mesothelioma | 0.00% | 1 in 106,571 | 2,552 | 563 new cases in the UK 2002(UK Government Statistics) |
| 573. Meningococcal disease | 0.00% | 1 in 108,756 | 2,500 | 2,501 annual cases notified in USA 1999 (MMWR 1999) |
| 574. Listeriosis | 0.00% | 1 in 108,800 | 2,500 | estimated 2,500 annually in USA (DBMD) |
| 575. Amputated toe | 0.00% | 1 in 111,223 | 2,445 | 41 annual cases in Victoria 1996 (DHS-VIC) |
| 576. Bone cancer | 0.00% | 1 in 113,333 | 2,400 | 2,400 annual cases (SEER 2002 estimate: bones and joints) |
| 577. Ureter cancer | 0.00% | 1 in 113,333 | 2,400 | 2,400 annual cases in USA (SEER 2002 estimate) |
| 578. Invasive group A Streptococcal disease | 0.00% | 1 in 114,189 | 2,382 | 2,382 annual cases notified in USA 1999 (MMWR 1999); 1.95 per 100,000 in Canada 20003 |
| 579. Cryptosporiosis | 0.00% | 1 in 115,205 | 2,360 | 2,361 annual cases notified in USA 1999 (MMWR 1999) |
| 580. Eye cancer | 0.00% | 1 in 123,636 | 2,200 | 2,200 annual cases (SEER 2002 estimate: eye and orbit) |
| 581. Amebiasis | 0.00% | 1 in 150,800 | 1,803 | 54 cases in NJ 1998 (NJ DHSS) |
| 582. Malaria | 0.00% | 1 in 151,111 | 1,800 | 1,800 cases annually (1997); 1,666 annual cases notified in USA 1999 (MMWR 1999) |
| 583. Huntington's Disease | 0.00% | 1 in 175,390 | 1,550 | 26 annual cases in Victoria 1996 (DHS-VIC) |
| 584. Cryptococcal Meningitis | 0.00% | 1 in 200,000 | 1,360 | about 5 per million |
| 585. Unexplained Illness | 0.00% | 1 in 200,000 | 1,360 | At least 0.5 cases per 100,000 (DBMD) |
| 586. Penis Cancer | 0.00% | 1 in 226,666 | 1,200 | 1,200 annual cases in USA (SEER 2002 estimate) |
| 587. Autoimmune Hepatitis | 0.00% | 1 in 235,294 | 1,156 | 1,156 people in the USA 1996 1 |
| 588. Legionnaires' disease | 0.00% | 1 in 245,487 | 1,107 | 1,108 annual cases notified in USA 1999 (MMWR 1999) |
| 589. Kawasaki disease | 0.00% | 1 in 271,440 | 1,002 | 30 cases in NJ 1998 (NJ DHSS) |
| 590. Thalassemia | 0.00% | 1 in 272,000 | 1,000 | 1,000 people with Cooley's anemia (NHLBI) |
| 591. Vibrio parahaemolyticus | 0.00% | 1 in 400,000 | 680 | 0.25 per 100,000 (DBMD 1997) |
| 592. Necrotizing fasciitis | 0.00% | 1 in 453,333 | 600 | 600 cases (DBMD) |
| 593. Rocky Mountain spotted fever | 0.00% | 1 in 469,775 | 578 | 579 annual cases notified in USA 1999 (MMWR 1999) |
| 594. Congenital syphilis | 0.00% | 1 in 489,208 | 556 | 556 annual cases notified in USA 1999 (MMWR 1999) |
| 595. Cryptococcosis | 0.00% | 1 in 500,000 | 544 | 0.2-0.9 cases per 100,000 in the general population (DBMD) |
| 596. SCID | 0.00% | 1 in 500,000 | 543 | approximately 1-per-500,000 (NIDCD); 1-per-million |
| 597. Amputated arm | 0.00% | 1 in 506,683 | 536 | 9 annual cases in Victoria 1996 (DHS-VIC) |
| 598. Lymphangioleiomyomatosis | 0.00% | 1 in 544,000 | 500 | Several hundred people in the USA (NHLBI) |
| 599. Nocardiosis | 0.00% | 1 in 544,000 | 500 | estimated 500-1,000 annual cases in USA (DBMD) |
| 600. Muscular Dystrophy | 0.00% | 1 in 651,450 | 417 | 7 annual cases in Victoria 1996 (DHS-VIC) |
| 601. Maternal death | 0.00% | 1 in 695,652 | 391 | 391 women in 1999 (NVSR Sep 2001) |
| 602. Mumps | 0.00% | 1 in 702,842 | 387 | 387 annual cases notified in USA 1999 (MMWR 1999); rare due to MMR vaccination |
| 603. Rubella | 0.00% | 1 in 747,252 | 364 | 364 cases annually (1998); incidence greatly reduced by MMR vaccination programs |
| 604. Typhoid fever | 0.00% | 1 in 786,127 | 346 | 346 annual cases notified in USA 1999 (MMWR 1999) |
| 605. Ehrlichiosis | 0.00% | 1 in 900,662 | 301 | 302 annual cases (203 of human granulocytic ehrlichiosis and 99 of human monocytic ehrlichiosis) notified in USA 1999 (MMWR 1999) |
| 606. Vibrio vulnificus | 0.00% | 1 in 906,666 | 300 | less than 300 cases in 1988-1995 (DBMD) |
| 607. Primary pulmonary hypertension | 0.00% | 1 in 906,666 | 300 | 300 new cases annually (NHLBI) |
| 608. Granuloma inguinale | 0.00% | 1 in 1 million | 272 | 0.1 new cases per 100,000 population of donovanosis was notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW) |
| 609. Arbovirus | 0.00% | 1 in 1 million | 272 | 0.1 new cases per 100,000 population of arbovirus infection was notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW) |
| 610. Hepatitis E | 0.00% | 1 in 1 million | 272 | 0.1 new cases per 100,000 population of Hepatitis E was notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW) |
| 611. Creutzfeldt-Jakob Disease | 0.00% | 1 in 1 million | 271 | 1-per-million |
| 612. Hemophilus influenzae B | 0.00% | 1 in 1 million | 260 | 261 annual cases of invasive HIB in USA 1999 (MMWR 1999) |
| 613. Vibrio | 0.00% | 1 in 1.2 million | 233 | 7 cases in NJ 1998 (NJ DHSS) |
| 614. Babesiosis | 0.00% | 1 in 1.2 million | 233 | 7 cases in NJ 1998 (NJ DHSS) |
| 615. Hemolytic uremic syndrome | 0.00% | 1 in 1.3 million | 201 | 202 cases of postdiarrheal HUS in 28 USA states 2001 (Morbidity and Mortality Weekly Report, 2003) |
| 616. Mucopolysaccharidosis I | 0.00% | 1 in 1.4 million | 200 | about 200 people ("Orphan Products: Hope for People With Rare Diseases", By Carol Rados, FDA Consumer magazine, November-December 2003 Issue) |
| 617. Botulism food poisoning | 0.00% | 1 in 1.8 million | 153 | 154 annual cases notified in USA 1999 including 23 foodborne, 92 infant, and 39 other (MMWR 1999) |
| 618. Chancroid | 0.00% | 1 in 1.9 million | 143 | 143 annual cases notified in USA 1999 (MMWR 1999); rare in the USA but with occasional outbreaks. |
| 619. Toxic Shock Syndrome | 0.00% | 1 in 2.4 million | 112 | 113 annual cases notified in USA 1999 (MMWR 1999); 1-2 per 100,000 (DBMD) |
| 620. Leprosy | 0.00% | 1 in 2.5 million | 108 | 108 annual cases notified in USA 1999 (MMWR 1999) |
| 621. Glucagonoma | 0.00% | 1 in 2.7 million | 100 | only 100 cases since 1974 (Ganda, 1997) |
| 622. Leptospirosis | 0.00% | 1 in 2.7 million | 100 | 100-200 cases annually in USA (DBMD) |
| 623. Measles | 0.00% | 1 in 2.7 million | 100 | 100 cases annually (1998); once common, now greatly reduced by MMR vaccination programs; 100 annual cases notified in USA 1999 (MMWR 1999) |
| 624. Dengue fever | 0.00% | 1 in 2.7 million | 100 | about 100 to 200 cases annually in USA (NIAID) |
| 625. POEMS | 0.00% | 1 in 2.7 million | 100 | about 100 known cases (Ganda [1997]) |
| 626. Infant botulism food poisoning | 0.00% | 1 in 2 million | 92 | 92 annual cases notified in USA 1999 (MMWR 1999) |
| 627. Brucellosis | 0.00% | 1 in 3.3 million | 82 | 82 annual cases notified in USA 1999 (MMWR 1999) |
| 628. Pregnancy-associated osteoporosis | 0.00% | 1 in 3.4 million | 80 | 80 annual cases (NWHIC) |
| 629. Encephalitis, California serogroup viral | 0.00% | 1 in 3.9 million | 70 | 70 annual cases notified in USA 1999 (MMWR 1999) |
| 630. Chronic Granulomatous Disease | 0.00% | 1 in 4 million | 67 | 1-in-4 million to 5 million (NIAID) |
| 631. Streptococcal Toxic Shock Syndrome | 0.00% | 1 in 4.5 million | 61 | 61 annual cases notified in USA 1999 (MMWR 1999) |
| 632. Cyclosporiasis | 0.00% | 1 in 4.9 million | 55 | 56 annual cases notified in USA 1999 (MMWR 1999) |
| 633. Rheumatic conditions | 0.00% | 1 in 6.3 million | 43 | nearly 43 Americans have arthritis or a rheumatic disease (CDC); 40 million people in the United States (NIAMS) |
| 634. Tetanus | 0.00% | 1 in 6.8 million | 40 | 40 annual cases notified in USA 1999 (MMWR 1999); rare due to vaccination. |
| 635. Hantavirus | 0.00% | 1 in 8.2 million | 32 | 33 annual cases of Hantavirus pulmonary syndrome notified in USA 1999 (MMWR 1999) |
| 636. Marine toxins | 0.00% | 1 in 9.1 million | 29 | approximately 30 cases annually in USA (DBMD) |
| 637. Baylisascaris | 0.00% | 1 in 9.1 million | 29 | fewer than 30 cases have been reported (DPD) |
| 638. East African Trypanosomiasis | 0.00% | 1 in 12 million | 21 | 21 cases in USA (DPD) |
| 639. Somatostatinoma | 0.00% | 1 in 13.6 million | 20 | 20 known cases in the literature (Ganda, 1997) |
| 640. Psittacosis | 0.00% | 1 in 17 million | 16 | 16 annual cases notified in USA 1999 (MMWR 1999) |
| 641. Trichinosis | 0.00% | 1 in 22.7 million | 11 | 12 annual cases notified in USA 1999 (MMWR 1999) |
| 642. Plague | 0.00% | 1 in 30.2 million | 9 | 9 annual cases of plague notified in USA 1999 (MMWR 1999) |
| 643. Rubella congenital syndrome | 0.00% | 1 in 30.2 million | 9 | 9 annual cases notified in USA 1999 (MMWR 1999) |
| 644. Cholera | 0.00% | 1 in 45.3 million | 5 | 6 annual cases notified in USA 1999 (MMWR 1999) |
| 645. Gastrointestinal Basidiobolomycosis | 0.00% | 1 in 45.3 million | 5 | 6 cases ever in history (CDC-OC) |
| 646. Eastern equine encephalitis | 0.00% | 1 in 54.4 million | 5 | 5 annual cases notified in USA 1999 (MMWR 1999) |
| 647. St. Louis encephalitis | 0.00% | 1 in 68 million | 4 | 4 annual cases notified in USA 1999 (MMWR 1999) |
| 648. Respiratory diphtheria | 0.00% | 1 in 100 million | 2 | Approximately 0.001 per 100,000 in USA (DBMD) |
| 649. Cutaneous diphtheria | 0.00% | 1 in 100 million | 2 | Approximately 0.001 cases per 100,000 population in the U.S. since 1980 (DBMD) |
| 650. Hydatidiform mole | 0.00% | 1 in 272 million | 1 | about 1 in 2000 pregnancies |
| 651. Diphtheria | 0.00% | 1 in 272 million | 1 | 1 annual case notified in USA 1999 (MMWR 1999) |
| 652. Yellow fever | 0.00% | 1 in 272 million | 1 | 1 annual case notified in USA 1999 (MMWR 1999) |
| 653. Pseudotumor Cerebri | 0.00% | 1 in 272 million | 1 | about 1-2 people per 100,000 population have benign intracranial hypertension in the US (Association for Spina Bifida and Hydrocephalus) |
| 654. Japanese encephalitis | 0.00% | 1 in 272 million | 1 | 1 case annually in USA (DVBID) |
| 655. Western equine encephalitis | 0.00% | 1 in 272 million | 1 | 1 annual cases notified in USA 1999 (MMWR 1999) |
| 656. Melioidosis | 0.00% | 1 in never | 0 | 0-5 cases annually (DBMD) |
| 657. Anthrax | 0.00% | 1 in never | 0 | 0 annual cases notified in USA 1999 (MMWR 1999) |
| 658. Polio | 0.00% | 1 in never | 0 | 0 annual cases of paralytic poliomyelitis notified in USA 1999 (MMWR 1999) |
| 659. Smallpox | 0.00% | 1 in never | 0 | 0 cases throughout the world. |
| 660. Lymphatic Filariasis | 0.00% | 1 in never | 0 | about 0 cases in the USA (DPD) |
| 661. Kuru | 0.00% | 1 in never | 0 | 0%; the disease is almost extinct. |
| 662. Glanders | 0.00% | 1 in never | 0 | 0 cases (CDC) |
| 663. Viral Hemorrhagic Fevers | 0.00% | 1 in never | 0 | 0 new cases of viral haemorrhagic fever per 100,000 population was notified in Australia 2002 (Yohannes K, Roche P, Blumer C et al. 2004, Australia’s Health 2004, AIHW) |
Footnotes:
1. Rose and Mackay, 1998, The Autoimmune Diseases, Third Edition
2. Childhood Symptoms, Edward R. Brace, John P. Pacanowski, Ed Weiner, 1992
3. Notifiable Diseases Online, PPHB, Canada, 2000
4. Pathophysiology of Disease, Stephen J. McPhee, Vishwanash R. Lingappa, Willim F. Ganong, Jack D. Lang, Prentice Hall, 1995
5. The Autoimmune Diseases, Noel R. Rose, Ian R. Mackay, 1998
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