Treatments for Malaria


Treatment list for Malaria: The list of treatments mentioned in various sources for Malaria includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

  • Hospitalization
  • Chloroquine - cheapest and most commonly used drug but many new strains are resistant.
  • Mefloquine
  • Quinine
  • Sulfadoxine/pyrimethamine combination
  • Quinine sulfate
  • Primaquine
  • Symptomatic relief
  • Sponging
  • Aspirin

Treatments of Malaria discussion: Resistance to chloroquine, once widely used and highly effective for preventing and treating malaria, has emerged in most parts of the world. Resistance to other antimalaria drugs also is widespread and growing. 1

Among the countries where the P. falciparum parasite causes malaria, only those of Central America have not recorded resistance to the drug chloroquine. The rapid evolution of such resistance in Africa increasingly complicates malaria treatment. Resistance to the drug combination sulfadoxine/pyrimethamine has developed in Southeast Asia, South America and Africa. In some areas of Thailand, more than 50 percent of cases no longer respond to mefloquine therapy. Sensitivity to quinine is diminishing in parts of Thailand and Vietnam. 2

Chloroquine is the cheapest (9 cents per dose) and most-used antimalarial drug, but resistance has made the drug virtually useless in East Africa and threatens its use in West African countries. WHO reports that only Central American countries have not reported chloroquine resistance. 2

1. excerpt from Antimicrobial Resistance, NIAID Fact Sheet: NIAID
2. excerpt from Malaria, NIAID Fact Sheet: NIAID

Last revision: June 2, 2003

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