Causes of Reiter’s syndrome


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Cause details for Reiter’s syndrome: When a preceding infection is recognized, symptoms of Reiter’s syndrome appear about 1 to 3 weeks after the infection. Chlamydia trachomatis is the bacteria most often associated with Reiter’s syndrome acquired through sexual contact. Several different bacteria are associated with Reiter’s syndrome acquired through the digestive tract, including Salmonella, Shigella, Yersinia, and Campylobacter. People may become infected with these bacteria after eating or handling improperly prepared food, such as meats that are not stored at the correct temperature.

Doctors do not know exactly why some people exposed to these bacteria develop the disorder and others do not, but they have identified a genetic factor (HLA–B27) that increases a person’s chance of developing Reiter’s syndrome. About 80 percent of people with Reiter’s syndrome are HLA–B27 positive. Only 6 percent of people who do not have the syndrome have the HLA–B27 gene.1

Underlying condition causes of Reiter’s syndrome: The list of possible underlying conditions (see also Misdiagnosis of underlying causes of Reiter’s syndrome) mentioned in various sources as possible causes of Reiter’s syndrome includes:

Related information for causes of Reiter’s syndrome: Further relevant information on causes of Reiter’s syndrome may be found in the risk factors for Reiter’s syndrome and underlying causes of Reiter’s syndrome.

Footnotes:
1. excerpt from Questions and Answers About Reiter's Syndrome: NIAMS

Last revision: June 12, 2003

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