Introduction: Sandhoff Disease

Sandhoff Disease: Rare genetic disease affecting the central nervous system.

Sandhoff Disease: Sandhoff disease is a rare, genetic, lipid storage disorder resulting in the progressive deterioration of the central nervous system. It is caused by a deficiency of the enzyme hexosaminidase which results in the accumulation of certain fats (lipids) in the brain and other organs of the body. Although Sandhoff disease is a severe form of Tay-Sachs disease—which is prevalent primarily in people of European Jewish descent—it is not limited to any ethnic group. Onset of the disorder usually occurs at 6 months of age. ¹

Researching symptoms of Sandhoff Disease: Further information about the symptoms of Sandhoff Disease is available including a list of symptoms of Sandhoff Disease, or alternatively return to research other symptoms in the symptom center.

Treatments for Sandhoff Disease: Various information is available about treatments available for Sandhoff Disease, or research treatments for other diseases.

Statistics and Sandhoff Disease: Various sources and calculations are available in statistics about Sandhoff Disease, prevalence and incidence statistics for Sandhoff Disease, and you can also research other medical statistics in our statistics center.

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